C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cadherin 3, type 1, P-cadherin (placental)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000062038 CDH3 9606 + 16:68636189-68722616 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264012 CDH3-001 68644836-68700295 protein_coding
  ENST00000429102 CDH3-002 68644993-68699036 protein_coding
  ENST00000542274 CDH3-003 68645301-68698692 nonsense_mediated_decay
  ENST00000565453 CDH3-004 68636189-68645318 processed_transcript
  ENST00000566808 CDH3-006 68645637-68679812 nonsense_mediated_decay
  ENST00000567674 CDH3-009 68687620-68698472 nonsense_mediated_decay
  ENST00000568292 CDH3-005 68691846-68696134 protein_coding
  ENST00000569036 CDH3-007 68678267-68682392 nonsense_mediated_decay
  ENST00000569080 CDH3-010 68695825-68722616 protein_coding
  ENST00000569117 CDH3-008 68696144-68696923 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264012ENST00000429102ENST00000542274ENST00000566808ENST00000567674ENST00000568292ENST00000569036ENST00000569117
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264012 0.115±0.00 N/A N/A N/A 0.305±0.00 0.056±0.00 0.035±0.00 0.018±0.00 0.053±0.02 0.065±0.00 0.006±0.00 N/A N/A 0.162±0.00
ENST00000429102 N/A 2.403±0.00 0.367±0.00 0.624±0.54 5.444±0.00 0.116±0.00 N/A 1.700±1.68 0.212±0.00 4.361±0.00 N/A 19.582±14.90 3.878±1.86 1.631±1.41
ENST00000542274 0.063±0.00 N/A N/A 0.314±0.00 2.033±0.00 N/A 0.180±0.00 1.262±0.00 N/A 0.149±0.00 N/A 12.742±5.43 7.804±0.00 1.226±0.39
ENST00000566808 N/A N/A N/A N/A 1.601±0.00 N/A N/A N/A N/A N/A 0.091±0.00 N/A N/A N/A
ENST00000567674 N/A 2.503±0.00 0.482±0.00 N/A 7.473±0.00 0.432±0.26 N/A N/A N/A 3.432±0.00 N/A 35.973±16.09 5.946±3.49 5.004±0.00
ENST00000568292 N/A N/A N/A 0.402±0.00 N/A N/A N/A N/A N/A 0.333±0.00 N/A N/A N/A N/A
ENST00000569036 N/A N/A N/A N/A N/A 0.312±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000569117 0.029±0.00 0.511±0.00 0.368±0.00 0.269±0.00 0.525±0.00 0.086±0.00 0.087±0.00 0.220±0.00 0.027±0.00 0.171±0.00 N/A 1.059±0.60 0.186±0.00 0.487±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004Y9 CIL_0004Y9_0003 CGP 16:68636189-68835548

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001895 IMP retina homeostasis
GO:0003674 ND molecular_function
GO:0005509 IEA calcium ion binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005913 IEA cell-cell adherens junction
GO:0007155 TAS cell adhesion
GO:0007156 IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007601 IEA visual perception
GO:0010628 IMP positive regulation of gene expression
GO:0010838 IMP positive regulation of keratinocyte proliferation
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016337 IEA single organismal cell-cell adhesion
GO:0022405 IMP hair cycle process
GO:0031424 IMP keratinization
GO:0032773 IMP positive regulation of monophenol monooxygenase activity
GO:0032912 IMP negative regulation of transforming growth factor beta2 production
GO:0034329 TAS cell junction assembly
GO:0034332 TAS adherens junction organization
GO:0042060 IEA wound healing
GO:0042493 IEA response to drug
GO:0043568 IMP positive regulation of insulin-like growth factor receptor signaling pathway
GO:0045216 TAS cell-cell junction organization
GO:0048023 IMP positive regulation of melanin biosynthetic process
GO:0051796 IMP negative regulation of catagen
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060901 IMP regulation of hair cycle by canonical Wnt signaling pathway
GO:1902910 IMP positive regulation of melanosome transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024371 cdh1 cadherin 1, epithelial protein_coding Danio_rerio
ENSDARG00000035796 si:ch211-206i14.2 si:ch211-206i14.2 protein_coding Danio_rerio
ENSDARG00000058546 si:dkey-30c15.12 si:dkey-30c15.12 protein_coding Danio_rerio
ENSDARG00000068137 si:dkey-173l11.5 si:dkey-173l11.5 protein_coding Danio_rerio
ENSDARG00000092450 si:dkey-173l11.3 si:dkey-173l11.3 protein_coding Danio_rerio
ENSMUSG00000061048 Cdh3 cadherin 3 protein_coding Mus_musculus

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