C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: U2 small nuclear RNA auxiliary factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000063244 U2AF2 9606 + 19:55654146-55674715 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308924 U2AF2-002 55655065-55674298 protein_coding
  ENST00000450554 U2AF2-001 55654146-55674715 protein_coding
  ENST00000587196 U2AF2-003 55655109-55661946 nonsense_mediated_decay
  ENST00000587275 U2AF2-009 55662519-55664059 retained_intron
  ENST00000588850 U2AF2-010 55655082-55661317 retained_intron
  ENST00000590551 U2AF2-008 55662499-55674239 protein_coding
  ENST00000592867 U2AF2-005 55659208-55660485 retained_intron
  ENST00000592874 U2AF2-007 55660516-55668865 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000308924ENST00000450554ENST00000590551
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000308924 12.619±0.00 23.232±0.00 N/A 8.734±0.00 7.833±5.68 N/A N/A N/A N/A 1.915±0.00 N/A 6.984±5.65 20.711±2.64 14.843±0.00
ENST00000450554 15.170±0.00 38.944±0.00 3.063±0.00 15.529±9.33 10.765±8.50 17.399±14.93 11.156±10.15 18.484±14.72 12.201±9.25 29.179±28.51 10.847±9.51 43.688±32.74 34.418±0.66 50.754±1.50
ENST00000590551 N/A N/A 1.679±0.00 N/A 7.408±0.00 11.533±5.65 1.229±0.00 11.093±8.17 4.252±0.00 5.459±0.00 5.166±2.12 49.848±51.57 45.797±27.06 88.203±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006S5 CIL_0006S5_0001 CGP 19:55641062-55674715
CIL_0003U5 CIL_0003U5_0001 CGP 19:55654146-55709858

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000398 IC mRNA splicing, via spliceosome
GO:0000974 IDA Prp19 complex
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005681 IDA spliceosomal complex
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006369 TAS termination of RNA polymerase II transcription
GO:0006397 TAS:IEA mRNA processing
GO:0006406 TAS mRNA export from nucleus
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0016607 IDA nuclear speck
GO:0019899 IPI enzyme binding
GO:0031124 TAS mRNA 3'-end processing
GO:0033120 IDA positive regulation of RNA splicing
GO:0044822 IDA poly(A) RNA binding
GO:0048025 IDA negative regulation of mRNA splicing, via spliceosome
GO:0070742 IEA C2H2 zinc finger domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011740 u2af2b U2 small nuclear RNA auxiliary factor 2b protein_coding Danio_rerio
ENSDARG00000012505 u2af2a U2 small nuclear RNA auxiliary factor 2a protein_coding Danio_rerio
ENSMUSG00000030435 U2af2 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 protein_coding Mus_musculus

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