C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAD18 E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070950 RAD18 9606 - 3:8775402-8963773 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264926 RAD18-001 8877076-8963502 protein_coding
  ENST00000413832 RAD18-007 8941796-8963773 protein_coding
  ENST00000415439 RAD18-002 8881264-8963431 nonsense_mediated_decay
  ENST00000418463 RAD18-010 8941531-8963470 protein_coding
  ENST00000421052 RAD18-009 8941551-8963470 protein_coding
  ENST00000427329 RAD18-008 8775402-8902456 protein_coding
  ENST00000429790 RAD18-003 8890109-8902398 protein_coding
  ENST00000469793 RAD18-005 8946952-8963443 retained_intron
  ENST00000473069 RAD18-004 8881420-8912469 retained_intron
  ENST00000495087 RAD18-006 8941513-8963502 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264926ENST00000415439ENST00000421052ENST00000495087
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264926 N/A 0.825±0.00 N/A 0.484±0.18 0.781±0.30 0.170±0.00 0.277±0.00 0.527±0.44 0.421±0.24 0.382±0.00 N/A 1.211±0.09 0.783±0.10 1.107±0.12
ENST00000415439 0.950±0.00 N/A 0.743±0.00 1.285±0.00 1.932±0.00 1.065±0.60 0.310±0.00 N/A 0.318±0.00 1.353±0.00 N/A 1.407±0.60 0.921±0.52 1.983±0.95
ENST00000421052 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.089±0.00 N/A N/A
ENST00000495087 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.259±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005S5 CIL_0005S5_0001 CGP 3:8619400-8841808
CIL_0003C9 CIL_0003C9_0001 CGP 3:8733800-8841808
CIL_0003CT CIL_0003CT_0001 CGP 3:8750408-8963773
CIL_0004QQ CIL_0004QQ_0001 CGP 3:8775402-9363053

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000403 IDA Y-form DNA binding
GO:0000785 IEA chromatin
GO:0001741 IEA XY body
GO:0003677 IEA DNA binding
GO:0003684 NAS damaged DNA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 NAS nucleus
GO:0005657 IDA replication fork
GO:0006281 NAS:IEA DNA repair
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007283 IEA spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0009411 IEA response to UV
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031593 IDA polyubiquitin binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0045910 IEA negative regulation of DNA recombination
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027938 rad18 RAD18 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000030254 Rad18 RAD18 homolog (S. cerevisiae) protein_coding Mus_musculus

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