C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ligand of numb-protein X 1, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072201 LNX1 9606 - 4:53459301-53701405 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263925 LNX1-001 53460456-53591616 protein_coding
  ENST00000306888 LNX1-002 53459301-53558217 protein_coding
  ENST00000504299 LNX1-004 53573984-53617501 protein_coding
  ENST00000504605 LNX1-005 53574057-53652477 processed_transcript
  ENST00000507168 LNX1-008 53573955-53652477 protein_coding
  ENST00000510143 LNX1-007 53573704-53652513 protein_coding
  ENST00000511398 LNX1-010 53498773-53508383 retained_intron
  ENST00000512247 LNX1-003 53573731-53591765 protein_coding
  ENST00000513421 LNX1-006 53573626-53701405 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainMuscleOvaryPlacentaENST00000263925ENST00000306888
Transcript ID Brain Muscle Ovary Placenta
ENST00000263925 N/A N/A N/A 12.572±2.02
ENST00000306888 10.660±3.63 1.576±0.00 5.467±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CS CIL_0001CS_0001 CGP 4:52872982-54295272
CIL_0007V9 CIL_0007V9_0001 VISTA 4:52895307-53499113
CIL_0001CL CIL_0001CL_0001 CGP 4:53377643-54295272
CIL_0001CM CIL_0001CM_0001 CGP 4:53459301-54064690

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008270 IEA zinc ion binding
GO:0016874 IEA ligase activity
GO:0030165 IEA PDZ domain binding
GO:0042787 IEA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0046872 IEA metal ion binding
GO:0051260 IEA protein homooligomerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043323 lnx1 ligand of numb-protein X 1 protein_coding Danio_rerio
ENSMUSG00000029228 Lnx1 ligand of numb-protein X 1 protein_coding Mus_musculus

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