C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fascin actin-bundling protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000075618 FSCN1 9606 + 7:5592823-5606655 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000382361 FSCN1-001 5592823-5606655 protein_coding
  ENST00000405801 FSCN1-005 5594686-5603998 protein_coding
  ENST00000444748 FSCN1-003 5593848-5603983 protein_coding
  ENST00000447103 FSCN1-004 5594547-5603946 protein_coding
  ENST00000473330 FSCN1-002 5602872-5606654 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000382361ENST00000405801ENST00000447103ENST00000473330
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000382361 27.833±0.00 36.026±0.00 0.564±0.00 33.331±23.09 15.129±13.23 2.922±2.28 2.391±2.19 6.151±2.99 3.894±2.27 16.948±15.14 0.649±0.50 122.022±104.22 100.865±11.55 42.976±20.25
ENST00000405801 N/A N/A 1.138±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000447103 N/A N/A N/A N/A N/A 0.566±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000473330 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.274±0.00 2.336±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000854 CIL_000854_0001 VISTA 7:5332287-5936913
CIL_0002V8 CIL_0002V8_0001 CGP 7:5527151-5606655
CIL_00027J CIL_00027J_0002 CGP 7:5592823-5781739

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 IDA stress fiber
GO:0003779 IDA actin binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0008144 IDA drug binding
GO:0008283 TAS cell proliferation
GO:0015629 IDA actin cytoskeleton
GO:0016477 IMP cell migration
GO:0030036 IDA actin cytoskeleton organization
GO:0030054 IEA cell junction
GO:0030175 IDA filopodium
GO:0030674 IEA protein binding, bridging
GO:0044822 IDA poly(A) RNA binding
GO:0048870 IDA cell motility
GO:0051015 IDA:IEA actin filament binding
GO:0051017 IDA actin filament bundle assembly
GO:0070062 IDA extracellular vesicular exosome
GO:0071437 IDA invadopodium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059680 fscn1a fascin homolog 1, actin-bundling protein a (Strongylocentrotus purpuratus) protein_coding Danio_rerio
ENSMUSG00000029581 Fscn1 fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) protein_coding Mus_musculus

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