C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029581 Fscn1 10090 + 5:142960343-142973185 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031565 Fscn1-001 142960343-142973185 protein_coding
  ENSMUST00000129306 Fscn1-002 142960843-142972170 protein_coding
  ENSMUST00000135293 Fscn1-006 142970085-142971989 retained_intron
  ENSMUST00000137552 Fscn1-005 142963250-142971953 protein_coding
  ENSMUST00000139131 Fscn1-004 142964533-142970674 protein_coding
  ENSMUST00000150622 Fscn1-003 142962953-142970552 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031565ENSMUST00000129306ENSMUST00000135293ENSMUST00000139131ENSMUST00000150622
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031565 46.051±4.44 35.226±4.26 33.424±2.27 167.319±84.32 95.986±30.15 9.485±0.93 12.094±1.67 9.077±0.94 8.697±8.83 9.146±1.34 2.751±1.39 88.217±34.87 81.661±34.20 1.804±1.31
ENSMUST00000129306 27.502±3.64 N/A N/A N/A 6.518±0.00 N/A 7.817±0.45 4.570±0.42 N/A N/A 1.972±0.00 33.137±11.47 99.574±49.44 3.136±0.21
ENSMUST00000135293 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 122.839±0.00 84.851±0.00 2.796±0.00
ENSMUST00000139131 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.418±0.34
ENSMUST00000150622 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.307±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000854 CIL_000854_0002 VISTA 5:142700569-143309825
CIL_0002V8 CIL_0002V8_0002 CGP 5:142903115-142973185
CIL_00027J CIL_00027J_0003 CGP 5:142960343-143113020

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001725 ISS stress fiber
GO:0003779 IDA actin binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0008144 IDA drug binding
GO:0015629 ISS actin cytoskeleton
GO:0016477 IMP cell migration
GO:0030036 IEA actin cytoskeleton organization
GO:0030054 IEA cell junction
GO:0030175 IDA filopodium
GO:0030674 IEA protein binding, bridging
GO:0044822 IEA poly(A) RNA binding
GO:0048870 ISS cell motility
GO:0051015 IMP actin filament binding
GO:0051017 IDA actin filament bundle assembly
GO:0070062 IEA extracellular vesicular exosome
GO:0071437 ISS invadopodium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059680 fscn1a fascin homolog 1, actin-bundling protein a (Strongylocentrotus purpuratus) protein_coding Danio_rerio
ENSG00000075618 FSCN1 fascin actin-bundling protein 1 protein_coding Homo_sapiens

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