C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cold inducible RNA binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000099622 CIRBP 9606 + 19:1259384-1274880 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320936 CIRBP-001 1269337-1273172 protein_coding
  ENST00000413636 CIRBP-008 1269332-1273172 protein_coding
  ENST00000444172 CIRBP-043 1271982-1274806 nonsense_mediated_decay
  ENST00000585630 CIRBP-037 1269266-1272582 protein_coding
  ENST00000585913 CIRBP-035 1267412-1274810 nonsense_mediated_decay
  ENST00000585914 CIRBP-007 1269352-1274773 nonsense_mediated_decay
  ENST00000586472 CIRBP-034 1266653-1273172 protein_coding
  ENST00000586548 CIRBP-021 1267339-1273172 protein_coding
  ENST00000586555 CIRBP-045 1273504-1274810 retained_intron
  ENST00000586636 CIRBP-033 1269347-1274880 nonsense_mediated_decay
  ENST00000586773 CIRBP-025 1269327-1274595 protein_coding
  ENST00000587169 CIRBP-004 1269335-1274810 nonsense_mediated_decay
  ENST00000587323 CIRBP-029 1269330-1272550 protein_coding
  ENST00000587896 CIRBP-032 1269337-1272550 protein_coding
  ENST00000588030 CIRBP-011 1259384-1273172 protein_coding
  ENST00000588090 CIRBP-018 1267088-1273172 protein_coding
  ENST00000588230 CIRBP-036 1269332-1272477 protein_coding
  ENST00000588344 CIRBP-017 1270943-1273104 protein_coding
  ENST00000588411 CIRBP-015 1261156-1271433 protein_coding
  ENST00000588917 CIRBP-044 1272925-1274810 retained_intron
  ENST00000589161 CIRBP-016 1261821-1264698 retained_intron
  ENST00000589235 CIRBP-006 1269350-1274810 protein_coding
  ENST00000589266 CIRBP-042 1266798-1271360 protein_coding
  ENST00000589686 CIRBP-031 1269331-1271995 protein_coding
  ENST00000589710 CIRBP-005 1269266-1273172 protein_coding
  ENST00000590171 CIRBP-030 1269356-1272374 nonsense_mediated_decay
  ENST00000590188 CIRBP-041 1272917-1274810 processed_transcript
  ENST00000590347 CIRBP-009 1269333-1274810 nonsense_mediated_decay
  ENST00000590704 CIRBP-003 1269332-1272777 retained_intron
  ENST00000591055 CIRBP-026 1269348-1272803 nonsense_mediated_decay
  ENST00000591097 CIRBP-010 1269332-1272604 nonsense_mediated_decay
  ENST00000591376 CIRBP-027 1269348-1274880 nonsense_mediated_decay
  ENST00000591622 CIRBP-022 1261342-1264572 retained_intron
  ENST00000591659 CIRBP-024 1269351-1271639 protein_coding
  ENST00000591935 CIRBP-020 1267229-1274480 protein_coding
  ENST00000592051 CIRBP-013 1261382-1271029 protein_coding
  ENST00000592234 CIRBP-039 1271030-1274810 nonsense_mediated_decay
  ENST00000592412 CIRBP-014 1269331-1272041 nonsense_mediated_decay
  ENST00000592467 CIRBP-012 1261166-1264572 retained_intron
  ENST00000592815 CIRBP-019 1267154-1271151 protein_coding
  ENST00000593048 CIRBP-028 1269336-1272600 nonsense_mediated_decay
  ENST00000593093 CIRBP-002 1269332-1274807 retained_intron
  ENST00000593128 CIRBP-023 1269331-1272552 retained_intron
  ENST00000593283 CIRBP-038 1269332-1272057 retained_intron
  ENST00000621399 CIRBP-040 1273554-1274805 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000320936ENST00000413636ENST00000585913ENST00000586472ENST00000587169ENST00000588230ENST00000589266ENST00000589710ENST00000593048ENST00000593093
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000320936 190.198±0.00 360.355±0.00 N/A 139.066±113.32 113.826±105.64 43.875±30.22 73.212±0.00 35.923±26.34 29.695±1.13 41.576±22.12 49.220±38.73 86.533±57.72 186.970±0.00 164.588±14.28
ENST00000413636 N/A N/A N/A N/A 2.234±0.00 N/A N/A 2.210±0.00 N/A N/A N/A N/A N/A N/A
ENST00000585913 N/A N/A N/A N/A N/A 121.742±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000586472 N/A N/A 15.037±0.00 N/A N/A N/A 9.699±0.00 N/A N/A N/A N/A 173.995±98.25 122.257±7.73 N/A
ENST00000587169 N/A N/A N/A N/A N/A N/A N/A 22.085±0.00 N/A N/A N/A 35.973±0.00 N/A N/A
ENST00000588230 N/A N/A 8.096±0.00 N/A 5.114±0.00 7.816±0.00 16.875±13.27 3.980±0.00 14.036±0.00 39.480±30.76 N/A 78.177±70.65 40.136±0.00 N/A
ENST00000589266 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 17.992±0.00 148.330±0.00 220.320±0.00 369.572±0.00
ENST00000589710 N/A N/A N/A N/A N/A N/A N/A 2.019±0.00 N/A N/A N/A N/A N/A N/A
ENST00000593048 N/A N/A N/A 179.414±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000593093 N/A N/A 2.183±0.00 N/A 0.894±0.00 1.707±0.00 0.806±0.00 N/A N/A 2.353±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000QP CIL_0000QP_0001 CGP 19:1248553-1274880
CIL_0000QS CIL_0000QS_0001 CGP 19:1259384-1279249

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0003676 IEA nucleic acid binding
GO:0003730 IDA mRNA 3'-UTR binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0009409 IEA response to cold
GO:0009411 IDA response to UV
GO:0010494 ISS cytoplasmic stress granule
GO:0017148 IEA negative regulation of translation
GO:0030371 ISS translation repressor activity
GO:0034063 ISS stress granule assembly
GO:0044822 IDA poly(A) RNA binding
GO:0045727 IDA positive regulation of translation
GO:0048255 IDA mRNA stabilization
GO:0070181 IDA small ribosomal subunit rRNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013351 cirbp cold inducible RNA binding protein protein_coding Danio_rerio
ENSDARG00000042049 protein_coding Danio_rerio
ENSMUSG00000045193 Cirbp cold inducible RNA binding protein protein_coding Mus_musculus

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