C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HMG box domain containing 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100281 HMGXB4 9606 + 22:35257452-35295807 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216106 HMGXB4-002 35257498-35295764 protein_coding
  ENST00000418170 HMGXB4-001 35257487-35295807 nonsense_mediated_decay
  ENST00000420166 HMGXB4-004 35257452-35265570 protein_coding
  ENST00000455359 HMGXB4-003 35257496-35265567 protein_coding
  ENST00000464480 HMGXB4-007 35262763-35264663 retained_intron
  ENST00000466438 HMGXB4-005 35257489-35258588 processed_transcript
  ENST00000498212 HMGXB4-008 35286882-35293028 retained_intron
  ENST00000498325 HMGXB4-006 35261854-35264052 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216106ENST00000418170ENST00000420166ENST00000464480
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216106 1.261±0.00 0.636±0.00 0.605±0.00 1.678±0.61 1.983±0.00 1.511±0.00 0.749±0.33 1.565±0.77 1.117±0.44 N/A 0.484±0.00 2.901±0.93 3.375±2.07 4.129±0.70
ENST00000418170 N/A 0.892±0.00 N/A N/A 0.636±0.00 0.871±0.00 N/A N/A N/A 0.180±0.00 1.291±0.00 1.512±0.80 N/A 2.380±0.05
ENST00000420166 N/A N/A 0.558±0.00 N/A N/A N/A N/A N/A 1.640±0.00 N/A 0.266±0.00 N/A N/A N/A
ENST00000464480 N/A N/A N/A N/A N/A N/A N/A 4.880±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NP CIL_0002NP_0001 CGP 22:35066136-35295807
CIL_0002NE CIL_0002NE_0001 CGP 22:35257452-35347994

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0008333 NAS endosome to lysosome transport
GO:0016055 IEA Wnt signaling pathway
GO:0016589 IDA NURF complex
GO:0030178 ISS negative regulation of Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075783 hmgxb4a HMG box domain containing 4a protein_coding Danio_rerio
ENSDARG00000091401 hmgxb4b HMG box domain containing 4b protein_coding Danio_rerio
ENSMUSG00000034518 Hmgxb4 HMG box domain containing 4 protein_coding Mus_musculus

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