C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: piezo-type mechanosensitive ion channel component 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000301015 PIEZO1-001 ENSG00000103335 9606 - 16:88715346-88785211 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301015
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301015 25.183±0.00 10.758±0.00 1.627±1.09 14.468±11.43 11.601±0.00 2.895±2.56 4.528±3.70 2.528±0.00 6.956±5.90 0.507±0.18 8.330±1.79 20.677±8.81 2.248±0.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091T CIL_00091T_0001 VISTA 16:88690989-89294615
CIL_0000Y8 CIL_0000Y8_0002 CGP 16:88696495-88715386
CIL_0000Y5 CIL_0000Y5_0002 CGP 16:88706463-88785211
CIL_00057I CIL_00057I_0002 CGP 16:88715343-88809258

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005261 ISS cation channel activity
GO:0005783 IDA endoplasmic reticulum
GO:0005886 ISS plasma membrane
GO:0006812 ISS cation transport
GO:0008381 IEA mechanically-gated ion channel activity
GO:0016021 IEA integral component of membrane
GO:0033625 IMP positive regulation of integrin activation
GO:0033634 IMP positive regulation of cell-cell adhesion mediated by integrin
GO:0034220 IEA ion transmembrane transport
GO:0042391 IEA regulation of membrane potential
GO:0050982 IEA detection of mechanical stimulus
GO:0098655 ISS cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000067252 Piezo1-201 protein_coding Mus_musculus 0 2964
ENSMUST00000156333 Piezo1-003 protein_coding Mus_musculus 0 2964
ENSMUST00000128383 Piezo1-001 nonsense_mediated_decay Mus_musculus 0 2916
ENSMUST00000148497 Piezo1-002 nonsense_mediated_decay Mus_musculus 0 2447
ENSDART00000113688 PIEZO2 (1 of 4)-201 protein_coding Danio_rerio 0 337
ENSDART00000153654 PIEZO2 (1 of 4)-001 protein_coding Danio_rerio 0 337
ENSMUST00000126553 Piezo1-007 retained_intron Mus_musculus 0 307
ENSMUST00000134304 Piezo1-006 retained_intron Mus_musculus 0 265
ENSMUST00000151855 Ctu2-002 nonsense_mediated_decay Mus_musculus 0 254
ENSMUST00000123671 Piezo1-008 retained_intron Mus_musculus 0 254
ENSMUST00000116412 Ctu2-001 protein_coding Mus_musculus 4e-20 106
ENSMUST00000046860 Piezo2-201 protein_coding Mus_musculus 4e-20 106
ENSMUST00000182166 Piezo2-007 protein_coding Mus_musculus 4e-20 106
ENSMUST00000182233 Piezo2-008 protein_coding Mus_musculus 4e-20 106
ENSMUST00000183217 Piezo2-005 protein_coding Mus_musculus 4e-20 106
ENSMUST00000047480 Piezo2-001 protein_coding Mus_musculus 4e-20 106

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