C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104728 ARHGEF10 9606 + 8:1823976-1958641 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000349830 ARHGEF10-003 1823976-1958633 protein_coding
  ENST00000382795 ARHGEF10-008 1858755-1869280 processed_transcript
  ENST00000398560 ARHGEF10-201 1858755-1904096 protein_coding
  ENST00000398564 ARHGEF10-202 1826111-1958633 protein_coding
  ENST00000518288 ARHGEF10-001 1824015-1958641 protein_coding
  ENST00000519641 ARHGEF10-010 1923196-1923874 retained_intron
  ENST00000520359 ARHGEF10-002 1823988-1958641 protein_coding
  ENST00000520972 ARHGEF10-006 1859894-1904110 retained_intron
  ENST00000521927 ARHGEF10-013 1943654-1957205 processed_transcript
  ENST00000522435 ARHGEF10-004 1882656-1958639 protein_coding
  ENST00000522969 ARHGEF10-007 1859915-1871131 retained_intron
  ENST00000523596 ARHGEF10-012 1943594-1952774 processed_transcript
  ENST00000523711 ARHGEF10-005 1876051-1927513 retained_intron
  ENST00000523980 ARHGEF10-011 1943595-1945919 retained_intron
  ENST00000524212 ARHGEF10-009 1904235-1923490 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000349830ENST00000398560ENST00000398564ENST00000519641ENST00000520359ENST00000520972ENST00000521927ENST00000522435ENST00000522969ENST00000523711
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000349830 1.388±0.00 2.091±0.00 0.691±0.00 3.581±0.00 2.054±0.00 2.016±1.62 1.612±1.37 1.825±0.00 1.037±0.89 1.373±0.63 0.217±0.00 2.174±1.87 1.078±0.41 6.586±0.30
ENST00000398560 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.321±0.00 N/A N/A N/A
ENST00000398564 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.923±0.00 N/A 0.919±0.09 0.854±0.00 9.097±0.00
ENST00000519641 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.732±0.00 N/A N/A N/A
ENST00000520359 2.505±0.00 N/A N/A N/A 1.160±0.01 N/A 1.408±0.85 N/A N/A 3.071±2.19 N/A 1.687±1.10 1.686±0.00 1.627±0.00
ENST00000520972 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.417±0.00 N/A 8.854±0.00
ENST00000521927 N/A N/A N/A N/A N/A 2.891±0.00 N/A N/A N/A N/A 1.602±0.00 N/A N/A N/A
ENST00000522435 1.767±0.00 4.196±0.00 N/A N/A 2.283±0.00 2.292±0.00 N/A 0.897±0.76 0.152±0.00 2.022±0.00 0.329±0.22 1.825±0.26 0.749±0.00 2.123±0.00
ENST00000522969 N/A N/A N/A 0.541±0.00 N/A N/A N/A N/A N/A N/A 0.332±0.00 N/A N/A N/A
ENST00000523711 N/A N/A 0.342±0.00 N/A N/A 0.326±0.00 N/A N/A N/A 1.109±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007GL CIL_0007GL_0002 CGP 8:1755778-1958641
CIL_0000LF CIL_0000LF_0001 CGP 8:1823976-2006936

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IDA:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI:IEA protein binding
GO:0005813 IDA centrosome
GO:0005829 NAS cytosol
GO:0019894 IPI kinesin binding
GO:0022011 IMP myelination in peripheral nervous system
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0033126 IDA positive regulation of GTP catabolic process
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0051298 IMP centrosome duplication
GO:0051496 IMP positive regulation of stress fiber assembly
GO:0090307 IMP spindle assembly involved in mitosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077788 arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 protein_coding Danio_rerio
ENSMUSG00000071176 Arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 protein_coding Mus_musculus

Loading