C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000071176 Arhgef10 10090 + 8:14911663-15001085 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000084207 Arhgef10-001 14911663-15001085 protein_coding
  ENSMUST00000110800 Arhgef10-002 14911738-15001085 protein_coding
  ENSMUST00000160619 Arhgef10-004 14911717-14928291 retained_intron
  ENSMUST00000161162 Arhgef10-003 14911724-14961202 protein_coding
  ENSMUST00000162444 Arhgef10-006 14990359-14991124 processed_transcript
  ENSMUST00000162636 Arhgef10-005 14996136-15001074 processed_transcript
  ENSMUST00000163062 Arhgef10-007 14945301-15001082 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000084207ENSMUST00000110800ENSMUST00000161162ENSMUST00000162636ENSMUST00000163062
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000084207 5.032±0.37 2.232±0.94 8.364±0.29 2.108±0.35 3.382±0.69 1.934±0.15 2.339±0.45 2.494±0.39 0.444±0.18 9.348±1.40 0.820±0.20 4.571±1.69 2.551±0.90 5.398±1.01
ENSMUST00000110800 8.271±2.37 2.974±0.98 4.606±0.17 3.248±1.56 6.124±1.86 2.931±0.97 2.465±0.86 1.038±0.32 0.515±0.20 6.986±1.25 0.476±0.25 5.932±2.26 4.931±2.17 2.626±1.15
ENSMUST00000161162 N/A N/A N/A 7.538±0.00 N/A N/A N/A N/A N/A N/A N/A 8.440±0.00 6.362±0.52 4.626±0.00
ENSMUST00000162636 N/A N/A 5.440±0.00 N/A N/A N/A 1.931±0.00 N/A 0.444±0.08 N/A 0.554±0.12 N/A N/A N/A
ENSMUST00000163062 N/A 3.268±1.70 N/A N/A 6.240±0.20 1.722±0.33 N/A N/A 0.269±0.09 4.098±0.40 N/A 4.195±1.75 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007GL CIL_0007GL_0003 CGP 8:14881335-15001085
CIL_0000LF CIL_0000LF_0002 CGP 8:14911663-15033333

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005813 IEA centrosome
GO:0019894 IEA kinesin binding
GO:0022011 IEA myelination in peripheral nervous system
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0033126 IEA positive regulation of GTP catabolic process
GO:0051298 IEA centrosome duplication
GO:0051496 IEA positive regulation of stress fiber assembly
GO:0090307 IEA spindle assembly involved in mitosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077788 arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 protein_coding Danio_rerio
ENSG00000104728 ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 protein_coding Homo_sapiens

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