C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 10
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000520359 ARHGEF10-002 ENSG00000104728 9606 + 8:1823988-1958641 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastHeartLungOvaryPlacentaTestisENST00000520359
Transcript ID Adipose Breast Heart Lung Ovary Placenta Testis
ENST00000520359 2.505±0.00 1.160±0.01 1.408±0.85 3.071±2.19 1.687±1.10 1.686±0.00 1.627±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007GL CIL_0007GL_0002 CGP 8:1755778-1958641
CIL_0000LF CIL_0000LF_0001 CGP 8:1823976-2006936

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IDA:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI:IEA protein binding
GO:0005813 IDA centrosome
GO:0005829 NAS cytosol
GO:0019894 IPI kinesin binding
GO:0022011 IMP myelination in peripheral nervous system
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0033126 IDA positive regulation of GTP catabolic process
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0051298 IMP centrosome duplication
GO:0051496 IMP positive regulation of stress fiber assembly
GO:0090307 IMP spindle assembly involved in mitosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000110800 Arhgef10-002 protein_coding Mus_musculus 0 2706
ENSMUST00000084207 Arhgef10-001 protein_coding Mus_musculus 0 2228
ENSMUST00000163062 Arhgef10-007 protein_coding Mus_musculus 0 1393
ENSMUST00000161162 Arhgef10-003 protein_coding Mus_musculus 0 743

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