C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106689 LHX2 9606 + 9:124001670-124033301 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373615 LHX2-001 124011610-124033301 protein_coding
  ENST00000446480 LHX2-002 124012357-124032884 protein_coding
  ENST00000488674 LHX2-003 124015397-124033301 protein_coding
  ENST00000560961 LHX2-004 124001670-124015361 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonHeartLiverLungOvaryPlacentaTestisENST00000373615ENST00000446480ENST00000488674ENST00000560961
Transcript ID Adipose Adrenal Brain Colon Heart Liver Lung Ovary Placenta Testis
ENST00000373615 N/A N/A 6.159±0.00 N/A N/A 0.671±0.00 N/A 0.032±0.00 0.274±0.00 0.505±0.12
ENST00000446480 N/A N/A N/A 0.219±0.00 0.049±0.00 N/A N/A 0.055±0.00 0.584±0.36 1.384±0.00
ENST00000488674 0.075±0.00 0.123±0.00 3.635±0.42 N/A 0.070±0.00 0.331±0.00 0.063±0.00 0.028±0.00 0.420±0.23 0.467±0.00
ENST00000560961 N/A N/A N/A N/A N/A N/A N/A N/A 1.912±0.00 2.369±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006WO CIL_0006WO_0001 CGP 9:123379654-124033301
CIL_000847 CIL_000847_0001 VISTA 9:123475439-124077650
CIL_0008FJ CIL_0008FJ_0001 VISTA 9:123533313-124136573
CIL_0007MV CIL_0007MV_0001 UCNEbase 9:123742251-124385977
CIL_0008N3 CIL_0008N3_0001 VISTA 9:123985007-124587009
CIL_0006WH CIL_0006WH_0001 CGP 9:124001670-124353307

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001076 IEA RNA polymerase II transcription factor binding transcription factor activity
GO:0001843 IEA neural tube closure
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007399 IEA nervous system development
GO:0007411 IEA axon guidance
GO:0007420 IEA brain development
GO:0007498 IEA mesoderm development
GO:0008270 IEA zinc ion binding
GO:0009953 IEA dorsal/ventral pattern formation
GO:0021537 IEA telencephalon development
GO:0021772 IEA olfactory bulb development
GO:0021978 IEA telencephalon regionalization
GO:0021987 IEA cerebral cortex development
GO:0022008 IEA neurogenesis
GO:0030182 IEA neuron differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048646 IEA anatomical structure formation involved in morphogenesis
GO:0048675 IEA axon extension
GO:0060041 IEA retina development in camera-type eye
GO:2000678 IEA negative regulation of transcription regulatory region DNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031222 lhx2b LIM homeobox 2b protein_coding Danio_rerio
ENSMUSG00000000247 Lhx2 LIM homeobox protein 2 protein_coding Mus_musculus

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