C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM homeobox protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000247 Lhx2 10090 + 2:38339281-38369733 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000253 Lhx2-001 38350759-38369733 protein_coding
  ENSMUST00000133661 Lhx2-005 38341092-38354825 protein_coding
  ENSMUST00000143783 Lhx2-003 38339281-38369199 protein_coding
  ENSMUST00000149664 Lhx2-004 38339488-38353693 retained_intron
  ENSMUST00000155964 Lhx2-002 38352532-38354573 protein_coding
  ENSMUST00000175896 Lhx2-006 38353802-38360089 retained_intron
  ENSMUST00000176229 Lhx2-007 38351768-38354631 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000000253ENSMUST00000133661ENSMUST00000143783ENSMUST00000149664ENSMUST00000155964ENSMUST00000175896
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000000253 0.017±0.01 0.020±0.01 0.005±0.00 15.924±8.74 0.409±0.09 0.058±0.04 0.020±0.01 0.036±0.02 1.739±0.53 0.009±0.00 0.013±0.00 0.141±0.10 2.024±1.17
ENSMUST00000133661 0.123±0.00 N/A 0.027±0.00 N/A 1.356±0.12 0.084±0.00 N/A N/A 1.593±0.12 N/A N/A 0.098±0.00 N/A
ENSMUST00000143783 N/A N/A N/A 17.166±2.46 N/A N/A N/A 0.033±0.00 N/A N/A 0.218±0.00 0.057±0.00 N/A
ENSMUST00000149664 N/A N/A 0.017±0.00 N/A N/A N/A N/A N/A N/A N/A 0.069±0.00 N/A N/A
ENSMUST00000155964 0.135±0.00 N/A N/A N/A N/A 0.613±0.00 N/A N/A N/A N/A N/A 0.157±0.00 N/A
ENSMUST00000175896 0.071±0.00 N/A 0.003±0.00 N/A N/A 0.019±0.00 N/A 0.021±0.00 N/A 0.036±0.00 N/A 0.033±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006WO CIL_0006WO_0002 CGP 2:37798991-38369733
CIL_000847 CIL_000847_0002 VISTA 2:37842558-38444874
CIL_0008FJ CIL_0008FJ_0002 VISTA 2:37895268-38499898
CIL_0007MV CIL_0007MV_0002 UCNEbase 2:38111928-38614796
CIL_0008N3 CIL_0008N3_0002 VISTA 2:38235055-38837083
CIL_00098L CIL_00098L_0002 VISTA 2:38294702-38895720
CIL_0006WH CIL_0006WH_0002 CGP 2:38339281-38588041

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001076 IPI RNA polymerase II transcription factor binding transcription factor activity
GO:0001843 IMP neural tube closure
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IDA nucleus
GO:0006366 IPI transcription from RNA polymerase II promoter
GO:0007399 IMP nervous system development
GO:0007411 IMP axon guidance
GO:0007420 IMP brain development
GO:0007498 IMP mesoderm development
GO:0008270 IEA zinc ion binding
GO:0009953 IMP dorsal/ventral pattern formation
GO:0021537 IMP telencephalon development
GO:0021772 IMP olfactory bulb development
GO:0021978 IGI telencephalon regionalization
GO:0021987 IMP cerebral cortex development
GO:0022008 IDA neurogenesis
GO:0030182 IMP neuron differentiation
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048646 IMP anatomical structure formation involved in morphogenesis
GO:0048675 IDA axon extension
GO:0060041 IGI retina development in camera-type eye
GO:2000678 IGI negative regulation of transcription regulatory region DNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031222 lhx2b LIM homeobox 2b protein_coding Danio_rerio
ENSG00000106689 LHX2 LIM homeobox 2 protein_coding Homo_sapiens

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