C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108671 PSMD11 9606 + 17:32444261-32483318 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261712 PSMD11-001 32444261-32483318 protein_coding
  ENST00000457654 PSMD11-004 32444474-32481471 protein_coding
  ENST00000469475 PSMD11-003 32480078-32480962 retained_intron
  ENST00000481992 PSMD11-005 32444512-32447333 retained_intron
  ENST00000493026 PSMD11-002 32476680-32481024 retained_intron
  ENST00000578213 PSMD11-007 32444379-32464561 protein_coding
  ENST00000578397 PSMD11-006 32444504-32477829 retained_intron
  ENST00000579451 PSMD11-008 32444505-32464567 protein_coding
  ENST00000580904 PSMD11-009 32445667-32454611 protein_coding
  ENST00000584340 PSMD11-010 32469072-32479282 nonsense_mediated_decay
  ENST00000585265 PSMD11-011 32480192-32480982 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261712ENST00000457654ENST00000469475ENST00000584340
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261712 13.584±0.00 N/A 2.811±0.00 7.799±3.37 2.958±0.66 5.296±1.35 3.369±2.42 4.861±0.70 6.193±0.00 5.162±3.75 7.342±2.91 11.998±4.67 11.314±4.58 12.574±1.47
ENST00000457654 18.469±0.00 13.441±0.00 N/A 4.186±2.02 6.789±4.67 6.111±1.97 7.604±5.63 6.942±4.88 10.500±0.00 8.164±4.04 27.399±24.72 8.346±3.24 11.241±2.62 10.772±3.00
ENST00000469475 N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.202±0.00 8.611±0.00 65.859±0.00 44.308±0.00 36.409±15.13
ENST00000584340 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 61.945±0.00 N/A 48.888±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000VN CIL_0000VN_0001 CGP 17:32350117-32483318
CIL_0005RM CIL_0005RM_0003 CGP 17:32444261-32491256

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005838 IEA proteasome regulatory particle
GO:0006511 IMP ubiquitin-dependent protein catabolic process
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0022624 IDA proteasome accessory complex
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043248 IMP proteasome assembly
GO:0044281 TAS small molecule metabolic process
GO:0048863 IMP stem cell differentiation
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005134 psmd11b proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b protein_coding Danio_rerio
ENSDARG00000060150 psmd11a proteasome (prosome, macropain) 216S subunit, non-ATPase, 11a protein_coding Danio_rerio
ENSMUSG00000017428 Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 protein_coding Mus_musculus

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