C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SUMO1/sentrin specific peptidase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112701 SENP6 9606 + 6:75601509-75718278 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000327284 SENP6-010 75601927-75678975 protein_coding
  ENST00000370010 SENP6-002 75601509-75715904 protein_coding
  ENST00000424947 SENP6-007 75633704-75679867 protein_coding
  ENST00000436928 SENP6-006 75646511-75663257 processed_transcript
  ENST00000447266 SENP6-004 75602047-75718278 protein_coding
  ENST00000474906 SENP6-009 75678811-75697989 retained_intron
  ENST00000476060 SENP6-008 75676604-75678975 retained_intron
  ENST00000483859 SENP6-003 75620663-75663514 protein_coding
  ENST00000485497 SENP6-012 75647292-75663505 retained_intron
  ENST00000487548 SENP6-005 75633650-75635056 retained_intron
  ENST00000493959 SENP6-001 75602224-75634811 nonsense_mediated_decay
  ENST00000503501 SENP6-011 75666871-75715877 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370010ENST00000424947ENST00000447266ENST00000503501
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370010 4.941±0.00 8.945±0.00 4.130±0.00 3.945±1.33 8.755±1.68 7.640±0.00 4.988±2.13 5.956±2.37 5.658±2.73 5.168±0.00 4.668±0.74 7.324±2.06 4.637±2.35 13.402±3.11
ENST00000424947 2.222±0.00 N/A N/A 3.803±0.80 N/A 3.582±0.00 N/A 2.703±0.00 N/A 2.004±0.00 N/A 2.825±0.00 1.004±0.00 N/A
ENST00000447266 0.751±0.00 N/A N/A N/A N/A 2.049±0.28 N/A N/A 1.829±1.46 0.990±0.00 0.921±0.00 2.863±0.00 0.488±0.00 1.842±0.00
ENST00000503501 3.405±0.00 7.009±0.00 N/A 3.068±0.00 5.050±0.00 4.174±0.00 N/A 5.951±2.82 1.684±0.00 6.162±3.45 N/A 7.299±0.82 3.611±1.13 9.831±0.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PT CIL_0006PT_0001 CGP 6:75291859-75718278
CIL_0006PS CIL_0006PS_0001 CGP 6:75601509-75919537

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0008234 IEA cysteine-type peptidase activity
GO:0016925 IEA protein sumoylation
GO:0016926 IMP protein desumoylation
GO:0016929 IMP SUMO-specific protease activity
GO:0070646 IDA protein modification by small protein removal
GO:0090169 IMP regulation of spindle assembly
GO:0090234 IMP regulation of kinetochore assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012493 senp6a SUMO1/sentrin specific peptidase 6a protein_coding Danio_rerio
ENSDARG00000079992 senp6b SUMO1/sentrin specific peptidase 6b protein_coding Danio_rerio
ENSMUSG00000034252 Senp6 SUMO/sentrin specific peptidase 6 protein_coding Mus_musculus

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