C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SUMO/sentrin specific peptidase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034252 Senp6 10090 + 9:80066903-80144953 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037484 Senp6-001 80066903-80144953 protein_coding
  ENSMUST00000164859 Senp6-002 80066973-80144168 protein_coding
  ENSMUST00000165607 Senp6-006 80067493-80143906 protein_coding
  ENSMUST00000175673 Senp6-003 80066903-80094484 retained_intron
  ENSMUST00000175722 Senp6-012 80139025-80143709 retained_intron
  ENSMUST00000175758 Senp6-008 80136373-80144171 retained_intron
  ENSMUST00000175910 Senp6-015 80114039-80122051 processed_transcript
  ENSMUST00000175999 Senp6-007 80067099-80144781 nonsense_mediated_decay
  ENSMUST00000176360 Senp6-005 80092303-80121979 protein_coding
  ENSMUST00000176527 Senp6-014 80123797-80136572 protein_coding
  ENSMUST00000176563 Senp6-013 80142045-80144005 retained_intron
  ENSMUST00000176607 Senp6-004 80103172-80143712 protein_coding
  ENSMUST00000176640 Senp6-009 80066936-80113753 protein_coding
  ENSMUST00000176648 Senp6-011 80114022-80118747 protein_coding
  ENSMUST00000177544 Senp6-010 80067817-80087498 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037484ENSMUST00000164859ENSMUST00000165607ENSMUST00000175673ENSMUST00000175758ENSMUST00000175999ENSMUST00000176360ENSMUST00000176607ENSMUST00000176640ENSMUST00000176648
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037484 1.341±0.70 N/A 1.260±0.16 3.157±0.43 1.500±0.48 1.829±0.70 0.770±0.13 1.933±0.50 1.081±0.43 2.762±0.69 0.967±0.10 1.868±0.60 1.274±0.09 N/A
ENSMUST00000164859 0.926±0.20 N/A 2.761±0.47 3.341±0.33 0.445±0.00 N/A 0.863±0.21 1.517±0.44 1.695±0.84 N/A 2.139±0.64 2.252±0.00 4.358±1.69 3.942±0.79
ENSMUST00000165607 1.877±0.14 N/A 3.605±1.31 8.566±6.56 0.697±0.11 N/A 0.795±0.19 N/A 2.469±0.67 N/A 3.357±0.56 22.786±6.74 11.772±7.10 6.090±4.15
ENSMUST00000175673 N/A 6.230±1.94 N/A N/A 5.300±1.91 3.674±1.95 N/A 3.100±0.00 N/A N/A N/A 8.381±3.97 N/A N/A
ENSMUST00000175758 1.942±0.22 N/A 5.150±0.04 4.295±0.00 2.635±1.25 N/A 3.090±0.34 4.695±1.28 2.911±1.13 5.605±0.00 4.256±0.84 21.070±6.82 8.607±5.16 N/A
ENSMUST00000175999 N/A N/A N/A N/A N/A N/A N/A 0.872±0.00 N/A 1.405±0.00 1.561±0.00 N/A N/A N/A
ENSMUST00000176360 N/A N/A N/A N/A 3.978±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000176607 1.554±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.256±0.00 N/A N/A
ENSMUST00000176640 3.166±0.47 5.434±0.56 N/A N/A 4.137±0.92 4.102±1.49 3.213±0.00 3.797±0.87 0.841±0.15 5.435±1.18 N/A 4.226±1.37 N/A 10.532±2.74
ENSMUST00000176648 N/A N/A N/A N/A N/A N/A N/A 5.345±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PT CIL_0006PT_0002 CGP 9:79815051-80144953
CIL_0006PS CIL_0006PS_0002 CGP 9:80066903-80311729

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006508 IEA proteolysis
GO:0008234 IEA cysteine-type peptidase activity
GO:0008270 IEA zinc ion binding
GO:0016925 IEA protein sumoylation
GO:0016926 ISS protein desumoylation
GO:0016929 ISS SUMO-specific protease activity
GO:0070646 ISS protein modification by small protein removal
GO:0090169 ISS regulation of spindle assembly
GO:0090234 ISS regulation of kinetochore assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012493 senp6a SUMO1/sentrin specific peptidase 6a protein_coding Danio_rerio
ENSDARG00000079992 senp6b SUMO1/sentrin specific peptidase 6b protein_coding Danio_rerio
ENSG00000112701 SENP6 SUMO1/sentrin specific peptidase 6 protein_coding Homo_sapiens

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