C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: drebrin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113758 DBN1 9606 - 5:177456608-177474401 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000292385 DBN1-002 177456927-177473198 protein_coding
  ENST00000309007 DBN1-001 177456608-177473741 protein_coding
  ENST00000393565 DBN1-004 177456936-177473637 protein_coding
  ENST00000467054 DBN1-012 177458297-177460642 retained_intron
  ENST00000471767 DBN1-007 177466831-177467598 retained_intron
  ENST00000472831 DBN1-003 177456934-177473624 retained_intron
  ENST00000477391 DBN1-009 177460432-177473613 protein_coding
  ENST00000505550 DBN1-010 177468553-177473622 retained_intron
  ENST00000506117 DBN1-011 177467490-177472870 protein_coding
  ENST00000512501 DBN1-006 177457367-177462413 protein_coding
  ENST00000514833 DBN1-008 177467586-177474401 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000292385ENST00000309007ENST00000393565ENST00000472831ENST00000477391
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000292385 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.707±0.00
ENST00000309007 8.570±0.00 7.535±0.00 N/A 3.916±2.23 8.082±0.00 0.723±0.00 2.648±0.00 7.571±0.00 1.701±1.48 3.097±2.17 1.205±0.00 23.148±13.69 2.159±0.00 6.426±3.09
ENST00000393565 N/A 5.455±0.00 N/A 17.009±8.75 4.313±2.55 14.125±0.00 N/A 0.155±0.00 3.345±0.00 0.824±0.00 2.966±1.47 12.951±0.00 6.026±0.00 12.280±0.00
ENST00000472831 19.605±0.00 10.248±0.00 N/A N/A 19.734±0.00 10.798±0.00 4.437±0.00 17.951±0.00 0.700±0.00 11.077±0.00 2.044±0.00 26.755±7.03 3.461±1.43 23.831±0.00
ENST00000477391 16.163±0.00 N/A 7.899±0.00 20.101±11.41 6.516±0.00 10.535±8.07 2.291±0.00 5.870±5.63 12.591±0.00 1.623±0.00 N/A 21.084±15.69 8.008±0.00 18.067±5.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A2 CIL_0008A2_0001 VISTA 5:177089375-177692188
CIL_0000XB CIL_0000XB_0002 CGP 5:177446445-177474401
CIL_0002YE CIL_0002YE_0001 CGP 5:177456608-177497606

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA:NAS actin binding
GO:0005515 IPI protein binding
GO:0005522 ISS profilin binding
GO:0005622 IEA intracellular
GO:0005737 NAS cytoplasm
GO:0005886 IEA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005921 IEA gap junction
GO:0007015 ISS actin filament organization
GO:0007399 IEA nervous system development
GO:0010643 IEA cell communication by chemical coupling
GO:0010644 IEA cell communication by electrical coupling
GO:0015629 ISS actin cytoskeleton
GO:0016020 IEA membrane
GO:0030425 NAS dendrite
GO:0032507 IEA maintenance of protein location in cell
GO:0042641 NAS actomyosin
GO:0048168 NAS regulation of neuronal synaptic plasticity
GO:0048699 IEA generation of neurons
GO:0050773 NAS regulation of dendrite development
GO:0061351 IEA neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069113 dbn1 drebrin 1 protein_coding Danio_rerio
ENSMUSG00000034675 Dbn1 drebrin 1 protein_coding Mus_musculus

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