C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: activating transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000123268 ATF1 9606 + 12:50763710-50821122 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262053 ATF1-001 50764292-50821122 protein_coding
  ENST00000549612 ATF1-005 50764078-50809475 nonsense_mediated_decay
  ENST00000551831 ATF1-002 50764480-50820010 nonsense_mediated_decay
  ENST00000552487 ATF1-004 50764509-50814368 protein_coding
  ENST00000552510 ATF1-003 50763710-50814192 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262053ENST00000549612ENST00000551831ENST00000552487ENST00000552510
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262053 6.297±0.00 3.358±0.00 1.052±0.00 2.012±0.00 1.857±0.36 5.330±0.00 1.715±0.82 4.487±3.24 1.347±0.00 3.664±0.00 2.496±1.92 3.686±0.78 3.305±0.20 2.098±0.33
ENST00000549612 N/A N/A 2.714±0.00 1.664±0.00 6.018±0.00 4.702±0.00 N/A N/A 3.454±0.00 3.395±0.00 12.990±0.00 5.983±0.00 N/A N/A
ENST00000551831 N/A N/A 1.628±0.00 N/A 1.176±0.00 N/A 2.030±0.00 7.520±0.00 N/A N/A 1.575±0.00 N/A N/A N/A
ENST00000552487 N/A N/A N/A N/A 2.676±0.00 N/A N/A N/A 2.764±0.00 N/A N/A 8.047±0.00 N/A 3.810±0.00
ENST00000552510 N/A N/A N/A 1.984±0.00 N/A N/A N/A N/A 3.703±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000062 CIL_000062_0001 CGP 12:50504985-50821122
CIL_00005M CIL_00005M_0001 CGP 12:50763710-50887884

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003677 IEA DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0010976 IEA positive regulation of neuron projection development
GO:0014070 IEA response to organic cyclic compound
GO:0032025 IEA response to cobalt ion
GO:0032403 IEA protein complex binding
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0043623 IEA cellular protein complex assembly
GO:0045087 TAS innate immune response
GO:0045740 IEA positive regulation of DNA replication
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051403 TAS stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044301 atf1 activating transcription factor 1 protein_coding Danio_rerio
ENSMUSG00000023027 Atf1 activating transcription factor 1 protein_coding Mus_musculus

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