C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: activating transcription factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000262053 ATF1-001 ENSG00000123268 9606 + 12:50764292-50821122 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262053
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262053 6.297±0.00 3.358±0.00 1.052±0.00 2.012±0.00 1.857±0.36 5.330±0.00 1.715±0.82 4.487±3.24 1.347±0.00 3.664±0.00 2.496±1.92 3.686±0.78 3.305±0.20 2.098±0.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000062 CIL_000062_0001 CGP 12:50504985-50821122
CIL_00005M CIL_00005M_0001 CGP 12:50763710-50887884

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003677 IEA DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0010976 IEA positive regulation of neuron projection development
GO:0014070 IEA response to organic cyclic compound
GO:0032025 IEA response to cobalt ion
GO:0032403 IEA protein complex binding
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0043623 IEA cellular protein complex assembly
GO:0045087 TAS innate immune response
GO:0045740 IEA positive regulation of DNA replication
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051403 TAS stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023769 Atf1-001 protein_coding Mus_musculus 0 953
ENSMUST00000120608 Gm1862-001 processed_pseudogene Mus_musculus 0 854
ENSMUST00000168103 Atf1-003 processed_transcript Mus_musculus 0 723
ENSMUST00000163855 Atf1-006 protein_coding Mus_musculus 0 630
ENSMUST00000172154 Atf1-005 protein_coding Mus_musculus 0 628
ENSMUST00000169408 Atf1-002 nonsense_mediated_decay Mus_musculus 0 573
ENSMUST00000166435 Atf1-009 protein_coding Mus_musculus 0 292
ENSMUST00000165804 Atf1-004 protein_coding Mus_musculus 0 265
ENSMUST00000166809 Atf1-007 retained_intron Mus_musculus 6e-18 97
ENSMUST00000171869 Atf1-008 protein_coding Mus_musculus 0.000000000000004 88

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