C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C and casein kinase substrate in neurons 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124507 PACSIN1 9606 + 6:34466061-34535231 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000244458 PACSIN1-001 34466139-34535231 protein_coding
  ENST00000374043 PACSIN1-003 34466139-34535229 protein_coding
  ENST00000486120 PACSIN1-005 34514889-34529552 processed_transcript
  ENST00000487760 PACSIN1-004 34514890-34527694 processed_transcript
  ENST00000493633 PACSIN1-002 34485070-34527714 processed_transcript
  ENST00000538621 PACSIN1-201 34514872-34535221 protein_coding
  ENST00000620693 PACSIN1-202 34466061-34535221 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000244458ENST00000374043ENST00000486120ENST00000493633ENST00000538621ENST00000620693
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000244458 0.003±0.00 N/A 0.005±0.00 N/A 0.009±0.00 N/A N/A 0.027±0.00 0.009±0.00 N/A 0.004±0.00 0.041±0.03 0.041±0.04 N/A
ENST00000374043 0.004±0.00 0.093±0.00 0.005±0.00 N/A 0.009±0.00 N/A N/A 0.029±0.00 0.020±0.01 N/A 0.005±0.00 0.086±0.01 0.054±0.05 N/A
ENST00000486120 N/A N/A N/A 11.971±0.00 N/A N/A 0.479±0.00 N/A N/A 0.394±0.00 N/A N/A 0.082±0.00 N/A
ENST00000493633 N/A N/A N/A N/A N/A N/A N/A N/A 0.151±0.00 0.985±0.00 N/A N/A 0.259±0.00 N/A
ENST00000538621 N/A N/A N/A 26.473±0.00 N/A 0.591±0.00 N/A N/A N/A N/A N/A 0.175±0.00 N/A N/A
ENST00000620693 0.003±0.00 0.151±0.00 0.002±0.00 33.239±15.22 0.061±0.06 N/A 1.982±0.00 0.408±0.40 0.021±0.02 0.169±0.00 0.004±0.00 0.107±0.00 0.028±0.00 0.516±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004LP CIL_0004LP_0002 CGP 6:34417454-34535231
CIL_0004LR CIL_0004LR_0002 CGP 6:34466061-34556333

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005543 IDA phospholipid binding
GO:0005737 IDA cytoplasm
GO:0005886 ISS plasma membrane
GO:0007015 IEA actin filament organization
GO:0008092 IEA cytoskeletal protein binding
GO:0030054 IEA cell junction
GO:0030137 IEA COPI-coated vesicle
GO:0031410 IEA cytoplasmic vesicle
GO:0032587 ISS ruffle membrane
GO:0043679 ISS axon terminus
GO:0045202 ISS synapse
GO:0045806 IEA negative regulation of endocytosis
GO:0048471 ISS perinuclear region of cytoplasm
GO:0048488 ISS synaptic vesicle endocytosis
GO:0048666 IEA neuron development
GO:0048812 ISS neuron projection morphogenesis
GO:0072657 ISS protein localization to membrane
GO:0090002 ISS establishment of protein localization to plasma membrane
GO:0097320 IDA membrane tubulation
GO:1900006 ISS positive regulation of dendrite development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032865 pacsin1a protein kinase C and casein kinase substrate in neurons 1a protein_coding Danio_rerio
ENSDARG00000042128 pacsin1b protein kinase C and casein kinase substrate in neurons 1b protein_coding Danio_rerio
ENSMUSG00000040276 Pacsin1 protein kinase C and casein kinase substrate in neurons 1 protein_coding Mus_musculus

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