C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tripartite motif containing 28
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000253024 TRIM28-001 ENSG00000130726 9606 + 19:58544469-58550716 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253024
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253024 20.511±0.00 27.634±0.00 12.737±11.40 14.850±12.56 29.798±27.58 14.778±13.10 39.926±0.00 10.356±7.14 24.220±22.79 38.512±35.91 76.163±38.91 42.951±33.83 50.574±17.66

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00070O CIL_00070O_0001 CGP 19:58513530-58550722
CIL_0006Z2 CIL_0006Z2_0001 CGP 19:58544091-58555124

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0001701 IEA in utero embryonic development
GO:0001837 ISS epithelial to mesenchymal transition
GO:0003677 IDA DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0003713 IEA transcription coactivator activity
GO:0003714 IDA transcription corepressor activity
GO:0004672 IEA protein kinase activity
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005719 IEA nuclear euchromatin
GO:0005720 IEA nuclear heterochromatin
GO:0006281 IDA DNA repair
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006468 IEA protein phosphorylation
GO:0007566 IEA embryo implantation
GO:0008270 IEA:IDA zinc ion binding
GO:0010467 TAS gene expression
GO:0016567 IDA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0016925 IEA protein sumoylation
GO:0031625 IDA ubiquitin protein ligase binding
GO:0035851 IDA Krueppel-associated box domain binding
GO:0042993 IDA positive regulation of transcription factor import into nucleus
GO:0043045 IEA DNA methylation involved in embryo development
GO:0043565 ISS sequence-specific DNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045087 IDA innate immune response
GO:0045739 IDA positive regulation of DNA repair
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046777 IEA protein autophosphorylation
GO:0051259 IDA protein oligomerization
GO:0060028 IEA convergent extension involved in axis elongation
GO:0060669 IEA embryonic placenta morphogenesis
GO:0070087 IPI chromo shadow domain binding
GO:1901536 IEA negative regulation of DNA demethylation
GO:1902187 IDA negative regulation of viral release from host cell
GO:2000653 IEA regulation of genetic imprinting

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005705 Trim28-001 protein_coding Mus_musculus 0 2830
ENSMUST00000128951 Trim28-004 retained_intron Mus_musculus 0 669
ENSMUST00000142421 Trim28-002 retained_intron Mus_musculus 0 667
ENSMUST00000123778 Trim28-009 retained_intron Mus_musculus 0 438
ENSMUST00000148354 Trim28-003 retained_intron Mus_musculus 0 285
ENSMUST00000129122 Trim28-008 retained_intron Mus_musculus 0 230

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