C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ribosomal RNA processing 8, methyltransferase, homolog (yeast)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132275 RRP8 9606 - 11:6595075-6603620 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254605 RRP8-001 6595075-6603620 protein_coding
  ENST00000526352 RRP8-004 6599943-6601304 retained_intron
  ENST00000530762 RRP8-006 6601254-6603597 nonsense_mediated_decay
  ENST00000533907 RRP8-002 6599943-6603604 nonsense_mediated_decay
  ENST00000534343 RRP8-003 6599920-6603579 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254605ENST00000530762ENST00000533907ENST00000534343
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254605 1.494±0.00 1.453±0.00 1.426±0.00 1.087±0.38 0.804±0.48 0.920±0.00 0.620±0.03 0.751±0.35 1.067±0.63 0.857±0.00 0.355±0.12 1.032±0.29 0.688±0.27 1.048±0.05
ENST00000530762 4.302±0.00 N/A N/A 1.006±0.00 2.501±0.00 5.287±0.00 2.382±1.31 3.328±1.33 1.956±0.65 2.996±1.80 1.406±0.97 3.353±0.36 3.496±0.52 4.337±0.60
ENST00000533907 N/A N/A N/A N/A 1.423±0.00 1.799±1.06 1.272±0.00 0.500±0.00 1.925±0.00 0.983±0.48 0.803±0.00 3.141±0.48 3.337±2.14 1.060±0.00
ENST00000534343 N/A 5.607±0.00 N/A N/A 3.239±0.00 3.924±0.00 N/A 5.171±0.00 4.347±0.00 3.533±0.00 3.565±0.00 6.397±0.00 5.017±0.06 3.393±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001I3 CIL_0001I3_0001 CGP 11:6497260-6603620
CIL_0001HZ CIL_0001HZ_0001 CGP 11:6595075-6610874

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000183 IDA chromatin silencing at rDNA
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005677 IDA chromatin silencing complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006364 IEA rRNA processing
GO:0008152 IEA metabolic process
GO:0008168 IEA methyltransferase activity
GO:0008757 TAS S-adenosylmethionine-dependent methyltransferase activity
GO:0016568 IEA chromatin modification
GO:0032259 IEA methylation
GO:0033553 IDA rDNA heterochromatin
GO:0035064 IDA methylated histone binding
GO:0042149 IMP cellular response to glucose starvation
GO:0044822 IDA poly(A) RNA binding
GO:0046015 IMP regulation of transcription by glucose
GO:0071158 IMP positive regulation of cell cycle arrest
GO:0072332 IMP intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071652 RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) protein_coding Danio_rerio
ENSMUSG00000030888 Rrp8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) protein_coding Mus_musculus

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