C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ribosomal RNA processing 8, methyltransferase, homolog (yeast)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000254605 RRP8-001 ENSG00000132275 9606 - 11:6595075-6603620 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254605
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254605 1.494±0.00 1.453±0.00 1.426±0.00 1.087±0.38 0.804±0.48 0.920±0.00 0.620±0.03 0.751±0.35 1.067±0.63 0.857±0.00 0.355±0.12 1.032±0.29 0.688±0.27 1.048±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001I3 CIL_0001I3_0001 CGP 11:6497260-6603620
CIL_0001HZ CIL_0001HZ_0001 CGP 11:6595075-6610874

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000183 IDA chromatin silencing at rDNA
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005677 IDA chromatin silencing complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006364 IEA rRNA processing
GO:0008152 IEA metabolic process
GO:0008168 IEA methyltransferase activity
GO:0008757 TAS S-adenosylmethionine-dependent methyltransferase activity
GO:0016568 IEA chromatin modification
GO:0032259 IEA methylation
GO:0033553 IDA rDNA heterochromatin
GO:0035064 IDA methylated histone binding
GO:0042149 IMP cellular response to glucose starvation
GO:0044822 IDA poly(A) RNA binding
GO:0046015 IMP regulation of transcription by glucose
GO:0071158 IMP positive regulation of cell cycle arrest
GO:0072332 IMP intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033179 Rrp8-001 protein_coding Mus_musculus 0 1184
ENSMUST00000098148 Rrp8-002 protein_coding Mus_musculus 0 1175
ENSMUST00000127738 Rrp8-004 processed_transcript Mus_musculus 0 569
ENSMUST00000154852 Rrp8-005 retained_intron Mus_musculus 0 545
ENSMUST00000148176 Rrp8-006 retained_intron Mus_musculus 1e-33 150

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