C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin, beta 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132470 ITGB4 9606 + 17:75721328-75757818 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000200181 ITGB4-001 75721436-75757818 protein_coding
  ENST00000449880 ITGB4-003 75724696-75757818 protein_coding
  ENST00000450894 ITGB4-002 75721497-75757815 protein_coding
  ENST00000578318 ITGB4-014 75757039-75757818 protein_coding
  ENST00000579211 ITGB4-013 75754483-75755778 retained_intron
  ENST00000579662 ITGB4-007 75721328-75757604 protein_coding
  ENST00000580542 ITGB4-004 75721509-75741105 retained_intron
  ENST00000582629 ITGB4-008 75727801-75757818 protein_coding
  ENST00000583327 ITGB4-011 75751813-75755808 protein_coding
  ENST00000584025 ITGB4-010 75742424-75749045 retained_intron
  ENST00000584374 ITGB4-009 75731820-75739905 processed_transcript
  ENST00000584558 ITGB4-005 75724704-75742657 processed_transcript
  ENST00000584939 ITGB4-012 75754618-75757002 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000200181ENST00000449880ENST00000450894ENST00000578318ENST00000579662ENST00000580542ENST00000582629ENST00000584558
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000200181 2.160±0.00 3.195±0.00 N/A 2.573±2.13 1.732±0.91 N/A N/A N/A 0.600±0.00 1.314±0.00 0.468±0.00 N/A N/A 1.323±0.00
ENST00000449880 8.662±0.00 N/A 0.318±0.00 7.068±0.00 N/A 13.185±0.00 1.918±0.00 1.224±0.00 0.111±0.00 3.613±1.66 0.718±0.00 5.887±0.15 N/A 0.639±0.00
ENST00000450894 N/A N/A N/A 5.935±0.00 N/A 4.080±0.00 N/A 0.881±0.00 N/A N/A N/A 2.922±1.46 49.208±11.58 N/A
ENST00000578318 N/A N/A N/A N/A N/A N/A N/A 0.363±0.00 N/A N/A N/A N/A N/A N/A
ENST00000579662 2.042±0.00 8.263±0.00 N/A 5.356±0.00 8.127±6.55 16.532±0.00 0.541±0.00 2.856±0.00 0.110±0.00 N/A N/A 10.050±7.85 18.241±9.53 2.193±1.96
ENST00000580542 N/A N/A 1.274±0.00 0.600±0.00 4.363±0.00 7.669±0.00 0.505±0.00 0.210±0.00 3.331±0.00 4.595±0.00 N/A 7.223±0.00 N/A N/A
ENST00000582629 N/A N/A N/A N/A N/A N/A N/A 0.381±0.00 N/A N/A N/A N/A N/A N/A
ENST00000584558 N/A N/A N/A 0.734±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002K8 CIL_0002K8_0002 CGP 17:75667116-75757818
CIL_00078P CIL_00078P_0001 CGP 17:75721328-75765711

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001664 IPI G-protein coupled receptor binding
GO:0004872 IEA receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005604 IEA basement membrane
GO:0005886 IDA plasma membrane
GO:0006914 IMP autophagy
GO:0007154 IEA cell communication
GO:0007155 NAS:IEA cell adhesion
GO:0007160 IMP:IEA cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0008305 IEA integrin complex
GO:0009611 IDA response to wounding
GO:0009925 IEA basal plasma membrane
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030056 IDA hemidesmosome
GO:0030198 TAS extracellular matrix organization
GO:0031252 IDA cell leading edge
GO:0031581 IDA:IEA hemidesmosome assembly
GO:0034329 TAS cell junction assembly
GO:0035878 IMP nail development
GO:0043235 IDA receptor complex
GO:0043588 IMP skin development
GO:0046847 IEA filopodium assembly
GO:0048333 IEP mesodermal cell differentiation
GO:0048565 IMP digestive tract development
GO:0048870 IMP:IEA cell motility
GO:0070062 IDA extracellular vesicular exosome
GO:0072001 IMP renal system development
GO:0097186 IMP amelogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028507 itgb4 integrin, beta 4 protein_coding Danio_rerio
ENSMUSG00000020758 Itgb4 integrin beta 4 protein_coding Mus_musculus

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