C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin beta 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020758 Itgb4 10090 + 11:115974709-116008412 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021107 Itgb4-001 115974709-116008412 protein_coding
  ENSMUST00000068981 Itgb4-002 115977786-116008412 protein_coding
  ENSMUST00000106458 Itgb4-004 115977786-116008412 protein_coding
  ENSMUST00000106460 Itgb4-003 115974979-116008412 protein_coding
  ENSMUST00000106461 Itgb4-201 115974725-116008411 protein_coding
  ENSMUST00000127523 Itgb4-007 115990952-115991973 processed_transcript
  ENSMUST00000130286 Itgb4-008 115992932-115994330 processed_transcript
  ENSMUST00000150129 Itgb4-006 115989938-115991050 processed_transcript
  ENSMUST00000151691 Itgb4-005 115974843-115994760 processed_transcript
  ENSMUST00000169928 Itgb4-202 115974725-116008411 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021107ENSMUST00000068981ENSMUST00000106458ENSMUST00000106460ENSMUST00000106461ENSMUST00000127523ENSMUST00000169928
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021107 N/A 0.462±0.04 2.669±1.23 N/A 1.127±0.00 N/A 0.293±0.00 0.489±0.10 0.025±0.00 N/A 0.133±0.00 1.072±0.00 1.132±0.55 N/A
ENSMUST00000068981 1.464±0.98 N/A 9.654±3.60 0.497±0.19 3.239±1.18 29.518±11.41 0.318±0.17 1.277±0.12 0.053±0.03 2.844±0.98 0.502±0.20 3.576±1.14 4.913±2.97 0.073±0.04
ENSMUST00000106458 N/A N/A N/A N/A N/A N/A N/A N/A 0.034±0.02 N/A 0.323±0.00 N/A N/A N/A
ENSMUST00000106460 0.988±0.44 1.103±0.00 N/A N/A 2.059±0.53 7.252±1.46 0.415±0.23 0.502±0.00 0.073±0.04 1.221±0.00 0.382±0.23 1.879±0.46 N/A N/A
ENSMUST00000106461 N/A 0.251±0.00 1.393±0.00 N/A N/A N/A N/A N/A N/A 0.495±0.00 N/A 0.800±0.00 N/A N/A
ENSMUST00000127523 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.588±0.00
ENSMUST00000169928 0.694±0.00 0.505±0.32 N/A 0.089±0.00 N/A N/A N/A N/A N/A 0.721±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002K8 CIL_0002K8_0003 CGP 11:115933282-116008412
CIL_00078P CIL_00078P_0002 CGP 11:115974709-116012719

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001664 IEA G-protein coupled receptor binding
GO:0004872 IEA receptor activity
GO:0005604 IDA basement membrane
GO:0005886 IEA plasma membrane
GO:0006914 IEA autophagy
GO:0007155 IMP cell adhesion
GO:0007160 IEA cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0008305 IDA integrin complex
GO:0009611 ISS response to wounding
GO:0009925 IDA basal plasma membrane
GO:0009986 IEA cell surface
GO:0030056 IDA hemidesmosome
GO:0031252 ISS cell leading edge
GO:0031581 IEA hemidesmosome assembly
GO:0035878 IEA nail development
GO:0043235 ISO receptor complex
GO:0043588 IEA skin development
GO:0046847 IMP filopodium assembly
GO:0048333 IEA mesodermal cell differentiation
GO:0048565 IEA digestive tract development
GO:0048870 IEA cell motility
GO:0070062 IEA extracellular vesicular exosome
GO:0072001 IEA renal system development
GO:0097186 IEA amelogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028507 itgb4 integrin, beta 4 protein_coding Danio_rerio
ENSG00000132470 ITGB4 integrin, beta 4 protein_coding Homo_sapiens

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