C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK2 homeobox 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136327 NKX2-8 9606 - 14:36580579-36582607 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258829 NKX2-8-001 36580579-36582607 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastLungOvaryTestisENST00000258829
Transcript ID Brain Breast Lung Ovary Testis
ENST00000258829 0.098±0.00 0.041±0.00 0.739±0.00 0.110±0.02 2.845±0.90

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00092P CIL_00092P_0001 VISTA 14:36045096-36646731
CIL_0008XR CIL_0008XR_0001 VISTA 14:36124115-36725121
CIL_0008R1 CIL_0008R1_0001 VISTA 14:36138356-36739990
CIL_00091S CIL_00091S_0001 VISTA 14:36141957-36745155
CIL_0007TC CIL_0007TC_0001 VISTA 14:36163945-36765327
CIL_0007XY CIL_0007XY_0001 VISTA 14:36204570-36805380
CIL_0007LS CIL_0007LS_0002 UCNEbase 14:36362793-37516218
CIL_0000SP CIL_0000SP_0001 CGP 14:36516392-36582607
CIL_00045C CIL_00045C_0001 CGP 14:36580579-36679715

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001889 NAS liver development
GO:0003677 IEA DNA binding
GO:0003690 IDA double-stranded DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005575 ND cellular_component
GO:0005634 IEA nucleus
GO:0006351 IDA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007409 IEA axonogenesis
GO:0030323 IEA respiratory tube development
GO:0030324 IEA lung development
GO:0043565 IDA sequence-specific DNA binding
GO:0050680 IEA negative regulation of epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052550 nkx2.2b NK2 transcription factor related 2b protein_coding Danio_rerio
ENSMUSG00000058669 Nkx2-9 NK2 homeobox 9 protein_coding Mus_musculus

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