C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transient receptor potential cation channel, subfamily C, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138741 TRPC3 9606 - 4:121879027-121951754 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264811 TRPC3-001 121879027-121933457 protein_coding
  ENST00000379645 TRPC3-002 121879028-121951754 protein_coding
  ENST00000502968 TRPC3-003 121932760-121950874 protein_coding
  ENST00000506449 TRPC3-004 121879716-121933113 nonsense_mediated_decay
  ENST00000513531 TRPC3-005 121879736-121933038 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264811ENST00000379645ENST00000506449ENST00000513531
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264811 N/A N/A N/A 0.902±0.00 N/A N/A N/A N/A 0.087±0.00 0.215±0.00 N/A N/A N/A N/A
ENST00000379645 0.046±0.00 N/A N/A 0.460±0.00 N/A 0.026±0.00 0.048±0.00 0.084±0.00 N/A 0.154±0.00 N/A 0.064±0.04 0.115±0.02 0.082±0.00
ENST00000506449 0.123±0.00 N/A 0.347±0.00 0.159±0.00 0.114±0.00 N/A N/A N/A 0.647±0.00 N/A 0.023±0.00 0.078±0.00 N/A 0.107±0.00
ENST00000513531 N/A 0.012±0.00 N/A N/A N/A N/A 0.013±0.00 0.082±0.04 N/A N/A N/A 0.042±0.00 0.145±0.10 0.128±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007AB CIL_0007AB_0001 CGP 4:121824440-121951754
CIL_0007AC CIL_0007AC_0001 CGP 4:121879027-122362758

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005262 IEA:TAS calcium channel activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0006816 TAS calcium ion transport
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0007602 TAS phototransduction
GO:0010524 IDA positive regulation of calcium ion transport into cytosol
GO:0015279 TAS store-operated calcium channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030168 TAS platelet activation
GO:0033198 IDA response to ATP
GO:0034220 TAS ion transmembrane transport
GO:0051592 IDA response to calcium ion
GO:0055085 TAS:IEA transmembrane transport
GO:0070588 IEA:IDA calcium ion transmembrane transport
GO:0070679 IDA inositol 1,4,5 trisphosphate binding
GO:1903244 IDA positive regulation of cardiac muscle hypertrophy in response to stress

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087463 TRPC3 transient receptor potential cation channel, subfamily C, member 3 protein_coding Danio_rerio
ENSMUSG00000027716 Trpc3 transient receptor potential cation channel, subfamily C, member 3 protein_coding Mus_musculus

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