C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain GRB2-like 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140600 SH3GL3 9606 + 15:83447228-83618743 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324537 SH3GL3-001 83447531-83618739 protein_coding
  ENST00000427482 SH3GL3-002 83447228-83618743 protein_coding
  ENST00000467735 SH3GL3-004 83609403-83618305 processed_transcript
  ENST00000492099 SH3GL3-003 83447228-83565883 retained_intron
  ENST00000563901 SH3GL3-005 83447376-83618739 nonsense_mediated_decay
  ENST00000564054 SH3GL3-006 83609270-83618642 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324537ENST00000427482ENST00000467735ENST00000492099ENST00000563901ENST00000564054
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324537 0.011±0.00 0.057±0.00 N/A N/A 0.005±0.00 0.045±0.00 0.016±0.00 0.200±0.00 0.161±0.13 0.132±0.00 0.047±0.00 0.088±0.04 N/A N/A
ENST00000427482 N/A N/A N/A 13.166±0.17 N/A 0.134±0.00 N/A N/A 0.780±0.00 N/A N/A 0.513±0.16 0.115±0.00 5.366±0.00
ENST00000467735 N/A N/A N/A N/A N/A N/A N/A 0.716±0.00 N/A N/A 0.305±0.00 N/A N/A N/A
ENST00000492099 N/A N/A N/A N/A N/A N/A 0.079±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000563901 N/A N/A N/A 17.450±6.74 N/A N/A N/A 0.447±0.00 N/A 0.532±0.39 N/A 0.099±0.06 0.918±0.74 7.578±0.00
ENST00000564054 N/A N/A 0.131±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.194±0.00 N/A 15.469±7.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KR CIL_0006KR_0001 CGP 15:83255903-83618743
CIL_0007U9 CIL_0007U9_0001 VISTA 15:83407808-84009696
CIL_000406 CIL_000406_0001 CGP 15:83447228-84039842

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0006897 IEA endocytosis
GO:0007165 TAS signal transduction
GO:0007417 TAS central nervous system development
GO:0008289 IEA lipid binding
GO:0016020 IEA membrane
GO:0042802 IPI identical protein binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007302 sh3gl3b SH3-domain GRB2-like 3b protein_coding Danio_rerio
ENSDARG00000013360 sh3gl3a SH3-domain GRB2-like 3a protein_coding Danio_rerio
ENSMUSG00000030638 Sh3gl3 SH3-domain GRB2-like 3 protein_coding Mus_musculus

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