C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain GRB2-like 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030638 Sh3gl3 10090 + 7:82173840-82307419 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032874 Sh3gl3-001 82174796-82307419 protein_coding
  ENSMUST00000177883 Sh3gl3-005 82174856-82307419 nonsense_mediated_decay
  ENSMUST00000177895 Sh3gl3-006 82174950-82307419 nonsense_mediated_decay
  ENSMUST00000178526 Sh3gl3-008 82270886-82307228 protein_coding
  ENSMUST00000179150 Sh3gl3-004 82175234-82176292 processed_transcript
  ENSMUST00000179318 Sh3gl3-002 82173840-82307087 protein_coding
  ENSMUST00000179800 Sh3gl3-009 82174842-82270038 retained_intron
  ENSMUST00000180183 Sh3gl3-007 82174195-82284095 protein_coding
  ENSMUST00000180243 Sh3gl3-003 82175156-82284158 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032874ENSMUST00000177883ENSMUST00000177895ENSMUST00000178526ENSMUST00000179318ENSMUST00000179800ENSMUST00000180183ENSMUST00000180243
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032874 0.962±0.02 0.336±0.14 7.606±0.31 6.178±1.18 0.264±0.05 1.290±0.00 0.131±0.00 0.153±0.00 0.026±0.01 0.241±0.09 0.047±0.00 0.479±0.35 0.354±0.12 23.784±2.66
ENSMUST00000177883 N/A 0.817±0.36 N/A N/A 0.270±0.16 0.870±0.00 0.314±0.17 0.079±0.02 0.030±0.00 N/A 0.036±0.00 0.468±0.34 0.569±0.00 N/A
ENSMUST00000177895 0.202±0.02 N/A 6.658±0.39 11.267±8.33 0.259±0.10 0.460±0.00 0.288±0.00 0.257±0.06 0.050±0.01 0.219±0.00 0.114±0.05 0.786±0.21 0.400±0.16 23.924±15.26
ENSMUST00000178526 N/A N/A N/A N/A 0.511±0.00 N/A N/A 0.114±0.02 N/A 0.296±0.02 0.025±0.00 0.301±0.00 N/A N/A
ENSMUST00000179318 N/A 0.197±0.10 N/A N/A 0.131±0.01 N/A N/A N/A N/A N/A N/A 0.530±0.04 0.209±0.00 23.087±23.42
ENSMUST00000179800 0.489±0.07 0.116±0.07 N/A N/A 0.071±0.03 0.113±0.08 0.047±0.01 N/A 0.018±0.00 0.057±0.03 0.022±0.00 0.241±0.17 0.097±0.00 5.639±0.99
ENSMUST00000180183 0.129±0.00 N/A N/A N/A N/A N/A 0.143±0.00 0.066±0.00 0.104±0.00 0.159±0.00 N/A 0.720±0.00 0.190±0.00 105.108±0.00
ENSMUST00000180243 N/A N/A N/A N/A N/A N/A N/A N/A 0.021±0.00 N/A 0.076±0.00 0.544±0.50 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KR CIL_0006KR_0002 CGP 7:81966672-82307419
CIL_0007U9 CIL_0007U9_0002 VISTA 7:82082717-82683985
CIL_000406 CIL_000406_0002 CGP 7:82173840-82614450

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0006897 IEA endocytosis
GO:0008289 IEA lipid binding
GO:0016020 IEA membrane
GO:0042802 IEA identical protein binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007302 sh3gl3b SH3-domain GRB2-like 3b protein_coding Danio_rerio
ENSDARG00000013360 sh3gl3a SH3-domain GRB2-like 3a protein_coding Danio_rerio
ENSG00000140600 SH3GL3 SH3-domain GRB2-like 3 protein_coding Homo_sapiens

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