C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: left-right determination factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143768 LEFTY2 9606 - 1:225936598-225941489 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000366820 LEFTY2-001 225936604-225941489 protein_coding
  ENST00000420304 LEFTY2-201 225936598-225941383 protein_coding
  ENST00000474493 LEFTY2-002 225939432-225940101 processed_transcript
  ENST00000616737 LEFTY2-202 225936628-225941173 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000366820ENST00000420304ENST00000616737
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000366820 N/A N/A N/A N/A N/A N/A N/A 0.682±0.00 N/A N/A N/A N/A
ENST00000420304 N/A 0.338±0.00 N/A 0.064±0.00 N/A N/A N/A N/A N/A 19.981±26.04 3.923±2.50 0.991±0.00
ENST00000616737 0.347±0.00 0.028±0.00 0.432±0.04 0.284±0.25 0.151±0.11 0.787±0.00 0.044±0.00 0.980±0.81 0.051±0.00 31.542±24.41 4.849±2.35 2.159±1.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007R5 CIL_0007R5_0001 VISTA 1:225466688-226068183
CIL_0005S0 CIL_0005S0_0001 CGP 1:225919877-225941489

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002576 TAS platelet degranulation
GO:0005125 IEA cytokine activity
GO:0005160 IEA transforming growth factor beta receptor binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0007596 TAS blood coagulation
GO:0008083 IEA growth factor activity
GO:0016049 IEA cell growth
GO:0030168 TAS platelet activation
GO:0031012 IDA extracellular matrix
GO:0031093 TAS platelet alpha granule lumen
GO:0040007 IEA growth

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019920 lft1 lefty1 protein_coding Danio_rerio
ENSDARG00000044059 lft2 lefty2 protein_coding Danio_rerio
ENSMUSG00000038793 Lefty1 left right determination factor 1 protein_coding Mus_musculus
ENSMUSG00000066652 Lefty2 left-right determination factor 2 protein_coding Mus_musculus

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