C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sodium channel, voltage-gated, type I, alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000144285 SCN1A 9606 - 2:165989160-166128013 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000303395 SCN1A-001 165989163-166073621 protein_coding
  ENST00000375405 SCN1A-002 165989163-166073639 protein_coding
  ENST00000409050 SCN1A-003 165991245-166073621 protein_coding
  ENST00000423058 SCN1A-201 165989160-166073697 protein_coding
  ENST00000473295 SCN1A-005 165996053-166000063 retained_intron
  ENST00000491429 SCN1A-004 165998125-166002908 retained_intron
  ENST00000507401 SCN1A-007 166073302-166128013 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartOvaryENST00000303395ENST00000375405ENST00000409050
Transcript ID Brain Heart Ovary
ENST00000303395 N/A 0.077±0.00 N/A
ENST00000375405 6.001±0.63 0.045±0.00 0.252±0.00
ENST00000409050 4.886±0.00 0.122±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006CL CIL_0006CL_0001 CGP 2:165857475-166128013
CIL_0006CK CIL_0006CK_0001 CGP 2:165989160-166375993

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001508 IEA action potential
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005216 IEA ion channel activity
GO:0005248 NAS:IEA voltage-gated sodium channel activity
GO:0005886 IBA plasma membrane
GO:0006811 IEA ion transport
GO:0006814 NAS:IEA sodium ion transport
GO:0007628 IEA adult walking behavior
GO:0014704 IEA intercalated disc
GO:0016020 IEA membrane
GO:0019227 IEA neuronal action potential propagation
GO:0019228 IBA neuronal action potential
GO:0030018 ISS Z disc
GO:0030315 IEA T-tubule
GO:0030424 IEA axon
GO:0033268 IEA node of Ranvier
GO:0034706 IEA sodium channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0042391 IEA regulation of membrane potential
GO:0043025 IEA neuronal cell body
GO:0043194 IEA axon initial segment
GO:0050884 IEA neuromuscular process controlling posture
GO:0055085 IEA transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010783 scn1a sodium channel, voltage-gated, type I, alpha protein_coding Danio_rerio
ENSDARG00000062744 scn1lab sodium channel, voltage-gated, type I like, alpha b protein_coding Danio_rerio
ENSMUSG00000064329 Scn1a sodium channel, voltage-gated, type I, alpha protein_coding Mus_musculus

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