C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glycine receptor, alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145888 GLRA1 9606 - 5:151822513-151924842 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000274576 GLRA1-001 151822513-151924842 protein_coding
  ENST00000455880 GLRA1-004 151822627-151924836 protein_coding
  ENST00000462581 GLRA1-002 151822627-151924836 nonsense_mediated_decay
  ENST00000471351 GLRA1-003 151849691-151924832 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverMuscleOvaryTestisENST00000462581ENST00000471351
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Testis
ENST00000462581 0.085±0.00 0.062±0.00 N/A N/A 0.059±0.00 N/A N/A 0.818±0.00 0.061±0.00 0.061±0.00
ENST00000471351 N/A 0.105±0.00 0.064±0.00 0.009±0.00 0.017±0.00 0.010±0.00 0.057±0.00 N/A N/A 0.087±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001U9 CIL_0001U9_0001 CGP 5:151771045-151924842
CIL_0001UA CIL_0001UA_0001 CGP 5:151822513-152433368

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001508 IEA action potential
GO:0001964 IMP startle response
GO:0002087 IEA regulation of respiratory gaseous exchange by neurological system process
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005886 TAS plasma membrane
GO:0005887 IMP integral component of plasma membrane
GO:0006810 IEA transport
GO:0006811 IDA:IEA ion transport
GO:0006821 IDA chloride transport
GO:0006936 IMP muscle contraction
GO:0007218 IDA neuropeptide signaling pathway
GO:0007268 IEA synaptic transmission
GO:0007340 IEA acrosome reaction
GO:0007601 IEA visual perception
GO:0007628 IEA adult walking behavior
GO:0009897 IEA external side of plasma membrane
GO:0016020 IEA membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0016594 IDA glycine binding
GO:0016934 IDA extracellular-glycine-gated chloride channel activity
GO:0022824 IEA transmitter-gated ion channel activity
GO:0030054 IEA cell junction
GO:0030977 IDA taurine binding
GO:0034220 TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0042391 IMP regulation of membrane potential
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043576 IEA regulation of respiratory gaseous exchange
GO:0045211 IEA postsynaptic membrane
GO:0050884 IEA neuromuscular process controlling posture
GO:0050905 IEA neuromuscular process
GO:0051970 IMP negative regulation of transmission of nerve impulse
GO:0055085 TAS transmembrane transport
GO:0060012 IEA synaptic transmission, glycinergic
GO:0060013 IEA righting reflex
GO:0060077 IEA inhibitory synapse
GO:0060080 IEA regulation of inhibitory postsynaptic membrane potential
GO:1902476 IEA chloride transmembrane transport
GO:2000344 IMP positive regulation of acrosome reaction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012019 glra1 glycine receptor, alpha 1 protein_coding Danio_rerio
ENSMUSG00000000263 Glra1 glycine receptor, alpha 1 subunit protein_coding Mus_musculus

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