C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor I/B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147862 NFIB 9606 - 9:14081843-14398983 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380921 NFIB-006 14305753-14313957 protein_coding
  ENST00000380924 NFIB-008 14088304-14180792 protein_coding
  ENST00000380934 NFIB-201 14081843-14398983 protein_coding
  ENST00000380953 NFIB-005 14087569-14313667 protein_coding
  ENST00000380959 NFIB-001 14081848-14313985 protein_coding
  ENST00000397575 NFIB-004 14087572-14314069 protein_coding
  ENST00000397579 NFIB-002 14087603-14314582 protein_coding
  ENST00000397581 NFIB-003 14087600-14314519 protein_coding
  ENST00000493697 NFIB-007 14307036-14308013 protein_coding
  ENST00000543693 NFIB-202 14081843-14180802 protein_coding
  ENST00000606230 NFIB-009 14307362-14322338 protein_coding
  ENST00000622101 NFIB-203 14081843-14314046 protein_coding
  ENST00000622520 NFIB-204 14305760-14313963 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380953ENST00000380959ENST00000397575ENST00000397579ENST00000543693ENST00000622101
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380953 N/A N/A 8.228±0.00 N/A N/A N/A N/A 5.619±0.00 N/A N/A 4.540±0.00 N/A N/A N/A
ENST00000380959 20.396±0.00 12.346±0.00 4.649±0.00 7.598±1.38 14.118±1.46 6.644±0.23 11.950±3.46 3.255±0.91 10.189±7.45 7.795±0.11 3.906±0.63 3.727±1.82 1.583±0.67 8.861±0.00
ENST00000397575 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.816±0.00 N/A N/A
ENST00000397579 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.327±0.00 2.179±0.00
ENST00000543693 N/A 5.325±0.00 N/A N/A 6.398±0.00 N/A N/A N/A 1.052±0.00 N/A N/A N/A 0.261±0.00 N/A
ENST00000622101 N/A N/A N/A N/A N/A N/A N/A 1.966±0.00 N/A N/A 3.073±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000746 CIL_000746_0001 CGP 9:13105704-14398983
CIL_0007VJ CIL_0007VJ_0001 VISTA 9:13639548-14240364
CIL_000143 CIL_000143_0001 CGP 9:14081843-14693471

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001106 IDA RNA polymerase II transcription corepressor activity
GO:0002062 ISS chondrocyte differentiation
GO:0003677 IDA DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005730 IDA nucleolus
GO:0006260 IEA DNA replication
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0008285 IEA negative regulation of cell proliferation
GO:0010001 ISS glial cell differentiation
GO:0021740 ISS principal sensory nucleus of trigeminal nerve development
GO:0021960 ISS anterior commissure morphogenesis
GO:0030324 IEA lung development
GO:0030900 IEA forebrain development
GO:0030902 IEA hindbrain development
GO:0043392 IDA negative regulation of DNA binding
GO:0044300 ISS cerebellar mossy fiber
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0060486 ISS Clara cell differentiation
GO:0060509 ISS Type I pneumocyte differentiation
GO:0060510 ISS Type II pneumocyte differentiation
GO:0061141 ISS lung ciliated cell differentiation
GO:0071679 ISS commissural neuron axon guidance
GO:2000791 ISS negative regulation of mesenchymal cell proliferation involved in lung development
GO:2000795 ISS negative regulation of epithelial cell proliferation involved in lung morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000008575 Nfib nuclear factor I/B protein_coding Mus_musculus

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