C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TIA1 cytotoxic granule-associated RNA binding protein-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151923 TIAL1 9606 - 10:119571802-119597029 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000369086 TIAL1-013 119581733-119588210 protein_coding
  ENST00000369087 TIAL1-002 119576776-119580782 retained_intron
  ENST00000369093 TIAL1-005 119571802-119596495 protein_coding
  ENST00000412524 TIAL1-012 119578767-119588357 protein_coding
  ENST00000436547 TIAL1-009 119575437-119596510 protein_coding
  ENST00000462373 TIAL1-011 119582531-119593494 processed_transcript
  ENST00000463089 TIAL1-004 119575219-119577214 processed_transcript
  ENST00000470635 TIAL1-001 119578747-119582184 processed_transcript
  ENST00000470781 TIAL1-008 119575425-119593513 retained_intron
  ENST00000479729 TIAL1-010 119588167-119596632 nonsense_mediated_decay
  ENST00000489822 TIAL1-006 119575399-119596964 retained_intron
  ENST00000495821 TIAL1-003 119577475-119578940 retained_intron
  ENST00000497671 TIAL1-007 119575412-119597029 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369093ENST00000436547ENST00000463089ENST00000470781ENST00000489822ENST00000497671
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369093 5.197±0.00 5.312±0.00 N/A 5.962±0.00 4.154±1.70 5.525±0.00 2.469±2.03 5.071±0.00 2.428±0.00 4.201±0.00 4.045±0.00 4.871±2.21 3.079±1.12 5.244±0.00
ENST00000436547 17.528±0.00 13.554±0.00 0.826±0.00 10.725±3.72 8.543±4.91 10.813±3.43 6.110±4.64 9.526±2.43 6.676±1.74 11.324±5.14 9.471±5.59 19.448±8.86 15.887±0.58 20.521±3.37
ENST00000463089 N/A N/A 3.614±0.00 N/A 6.788±0.00 4.022±0.00 2.158±0.00 N/A 4.728±0.00 N/A N/A N/A N/A N/A
ENST00000470781 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.213±0.00 N/A N/A N/A N/A
ENST00000489822 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.356±0.00 2.453±0.00 N/A
ENST00000497671 N/A N/A 0.652±0.00 N/A 2.727±0.00 N/A N/A N/A N/A N/A N/A 7.169±1.23 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003IZ CIL_0003IZ_0001 CGP 10:119499828-119597029
CIL_0004GP CIL_0004GP_0002 CGP 10:119571802-119677819

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0003676 IEA nucleic acid binding
GO:0003723 TAS RNA binding
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005764 TAS lysosome
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006915 IEA apoptotic process
GO:0006952 TAS defense response
GO:0007281 IEA germ cell development
GO:0008284 IEA positive regulation of cell proliferation
GO:0010494 ISS cytoplasmic stress granule
GO:0017091 IEA AU-rich element binding
GO:0017145 IEA stem cell division
GO:0044822 IDA poly(A) RNA binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009525 tial1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 protein_coding Danio_rerio
ENSMUSG00000030846 Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 protein_coding Mus_musculus

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