C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152377 SPOCK1 9606 - 5:136975298-137598379 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282223 SPOCK1-201 136975300-137267065 protein_coding
  ENST00000394945 SPOCK1-001 136975298-137499348 protein_coding
  ENST00000503916 SPOCK1-002 137112494-137598379 processed_transcript
  ENST00000505690 SPOCK1-003 137112492-137498594 protein_coding
  ENST00000508642 SPOCK1-007 136988553-136993160 processed_transcript
  ENST00000509293 SPOCK1-005 137267015-137365461 processed_transcript
  ENST00000509978 SPOCK1-008 136978792-136988837 processed_transcript
  ENST00000510405 SPOCK1-006 137112435-137313538 protein_coding
  ENST00000510689 SPOCK1-004 136992554-137499299 protein_coding
  ENST00000515091 SPOCK1-009 136978454-136979500 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000282223ENST00000394945ENST00000505690ENST00000509978ENST00000510405ENST00000515091
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000282223 N/A 0.398±0.00 0.806±0.00 N/A 0.879±0.00 0.103±0.00 N/A 0.014±0.00 N/A 0.139±0.00 N/A 0.306±0.00 2.976±0.02 N/A
ENST00000394945 37.015±0.00 0.459±0.00 0.866±0.00 37.848±29.92 2.617±0.71 16.926±0.00 2.557±2.09 11.322±0.00 2.749±0.00 0.473±0.00 10.407±0.00 0.730±0.00 3.855±2.75 7.321±0.00
ENST00000505690 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.290±0.00 N/A N/A N/A N/A
ENST00000509978 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.441±0.00 N/A N/A N/A
ENST00000510405 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.377±0.00 N/A N/A N/A N/A
ENST00000515091 N/A N/A N/A N/A N/A N/A N/A 0.062±0.00 N/A N/A N/A 0.431±0.00 12.846±0.00 9.163±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005P0 CIL_0005P0_0001 CGP 5:136213320-137598379
CIL_0005P1 CIL_0005P1_0001 CGP 5:136975298-137736090

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 NAS regulation of cell growth
GO:0001764 ISS neuron migration
GO:0004867 NAS serine-type endopeptidase inhibitor activity
GO:0004869 IDA cysteine-type endopeptidase inhibitor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0005737 ISS cytoplasm
GO:0007155 NAS cell adhesion
GO:0007165 IEA signal transduction
GO:0007399 NAS nervous system development
GO:0008191 IDA metalloendopeptidase inhibitor activity
GO:0010812 IDA negative regulation of cell-substrate adhesion
GO:0010951 IDA negative regulation of endopeptidase activity
GO:0010977 IDA negative regulation of neuron projection development
GO:0014069 NAS postsynaptic density
GO:0016528 ISS sarcoplasm
GO:0021953 ISS central nervous system neuron differentiation
GO:0022008 ISS neurogenesis
GO:0031594 ISS neuromuscular junction
GO:0033268 ISS node of Ranvier

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074644 SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 protein_coding Danio_rerio
ENSMUSG00000056222 Spock1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 protein_coding Mus_musculus

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