C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000153707 PTPRD 9606 - 9:8314246-10612723 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355233 PTPRD-201 8314247-8733946 protein_coding
  ENST00000356435 PTPRD-202 8314247-8733949 protein_coding
  ENST00000381196 PTPRD-002 8314246-10033790 protein_coding
  ENST00000397606 PTPRD-006 8317405-8733894 protein_coding
  ENST00000397611 PTPRD-203 8314247-8733949 protein_coding
  ENST00000397617 PTPRD-204 8314247-8733946 protein_coding
  ENST00000463477 PTPRD-001 8528152-10612723 protein_coding
  ENST00000471274 PTPRD-005 8485763-8501059 processed_transcript
  ENST00000477552 PTPRD-007 8484238-8485636 retained_intron
  ENST00000481079 PTPRD-008 8633390-8857776 protein_coding
  ENST00000486161 PTPRD-003 8317404-8733894 protein_coding
  ENST00000488774 PTPRD-004 8524949-8633460 processed_transcript
  ENST00000537002 PTPRD-205 8314247-8733949 protein_coding
  ENST00000540109 PTPRD-206 8317277-8733949 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356435ENST00000381196ENST00000397606ENST00000397611ENST00000397617ENST00000471274ENST00000537002ENST00000540109
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356435 N/A 0.071±0.00 N/A N/A 0.122±0.04 N/A N/A 1.109±0.00 N/A 1.082±0.00 N/A 1.564±1.55 0.696±0.00 N/A
ENST00000381196 N/A N/A N/A 3.185±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000397606 N/A N/A 1.577±0.00 5.416±1.05 N/A N/A 0.277±0.14 0.741±0.00 1.219±0.00 N/A 0.055±0.00 0.413±0.00 N/A 0.585±0.00
ENST00000397611 N/A N/A N/A 4.566±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000397617 N/A 0.231±0.00 N/A 3.917±0.00 N/A N/A 0.412±0.00 N/A 0.195±0.00 0.358±0.00 N/A 0.731±0.00 0.754±0.45 N/A
ENST00000471274 N/A N/A N/A N/A N/A 4.445±0.00 N/A N/A N/A N/A 0.319±0.00 N/A N/A N/A
ENST00000537002 0.084±0.00 N/A N/A 5.266±0.33 0.184±0.02 N/A N/A N/A N/A N/A N/A N/A 0.385±0.00 0.370±0.00
ENST00000540109 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.031±0.00 N/A 1.136±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007VK CIL_0007VK_0001 VISTA 9:7795553-8396166
CIL_0003OT CIL_0003OT_0001 CGP 9:7796490-10612723
CIL_0007LL CIL_0007LL_0001 UCNEbase 9:8095704-8526809
CIL_0005UW CIL_0005UW_0002 CGP 9:8314246-12710290

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005001 TAS transmembrane receptor protein tyrosine phosphatase activity
GO:0005102 ISS receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005887 TAS integral component of plasma membrane
GO:0006470 TAS:IEA protein dephosphorylation
GO:0006796 NAS phosphate-containing compound metabolic process
GO:0007157 ISS heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007185 TAS transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0030182 ISS neuron differentiation
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0050775 ISS positive regulation of dendrite morphogenesis
GO:0050839 ISS cell adhesion molecule binding
GO:0070062 IDA extracellular vesicular exosome
GO:0097105 ISS presynaptic membrane assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019945 ptprdb protein tyrosine phosphatase, receptor type, D, b protein_coding Danio_rerio
ENSMUSG00000028399 Ptprd protein tyrosine phosphatase, receptor type, D protein_coding Mus_musculus

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