C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028399 Ptprd 10090 - 4:75941238-78211961 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050757 Ptprd-009 75944958-76344243 protein_coding
  ENSMUST00000084467 Ptprd-010 76140358-76325288 processed_transcript
  ENSMUST00000098005 Ptprd-015 75944958-76325264 protein_coding
  ENSMUST00000102834 Ptprd-004 75941239-76133882 protein_coding
  ENSMUST00000107287 Ptprd-002 76139382-78211895 processed_transcript
  ENSMUST00000107289 Ptprd-001 75941238-76449980 protein_coding
  ENSMUST00000129550 Ptprd-007 77917524-78211852 processed_transcript
  ENSMUST00000134604 Ptprd-008 77925213-78211843 retained_intron
  ENSMUST00000138955 Ptprd-006 76593551-78211739 processed_transcript
  ENSMUST00000140422 Ptprd-003 77351290-78211961 processed_transcript
  ENSMUST00000156656 Ptprd-005 76591325-78211867 processed_transcript
  ENSMUST00000172811 Ptprd-019 76099412-76107395 nonsense_mediated_decay
  ENSMUST00000173376 Ptprd-018 75944806-76594299 protein_coding
  ENSMUST00000173560 Ptprd-011 76082247-76101444 retained_intron
  ENSMUST00000173592 Ptprd-020 77193100-78211739 retained_intron
  ENSMUST00000173662 Ptprd-017 76084371-76086516 protein_coding
  ENSMUST00000174023 Ptprd-016 75944958-76325264 protein_coding
  ENSMUST00000174180 Ptprd-014 75944958-76325264 protein_coding
  ENSMUST00000174531 Ptprd-021 75944958-76325264 protein_coding
  ENSMUST00000174831 Ptprd-013 75944958-76325243 protein_coding
  ENSMUST00000174832 Ptprd-012 76133158-76134143 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000050757ENSMUST00000102834ENSMUST00000107287ENSMUST00000107289ENSMUST00000173376ENSMUST00000174180ENSMUST00000174531ENSMUST00000174831
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000050757 N/A N/A N/A N/A 0.894±0.00 N/A N/A N/A 2.277±0.00 N/A N/A N/A N/A 0.437±0.00
ENSMUST00000102834 N/A N/A 0.556±0.20 18.528±10.77 N/A N/A N/A N/A 0.901±0.78 N/A 0.120±0.04 N/A 0.098±0.07 0.238±0.00
ENSMUST00000107287 N/A 3.064±0.56 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000107289 2.445±1.06 1.615±0.58 0.618±0.07 8.749±4.16 2.291±0.21 N/A 0.480±0.27 5.522±1.33 1.525±1.22 4.246±0.53 0.176±0.06 5.591±1.71 N/A 0.474±0.07
ENSMUST00000173376 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.471±0.00
ENSMUST00000174180 1.754±0.39 2.087±0.82 N/A N/A 1.438±0.66 2.085±0.30 0.517±0.08 4.980±1.77 1.323±0.92 2.067±0.19 0.234±0.00 8.348±5.18 0.132±0.00 1.117±0.28
ENSMUST00000174531 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.271±0.00 N/A N/A
ENSMUST00000174831 N/A N/A N/A 15.448±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OT CIL_0003OT_0002 CGP 4:75277354-78211961
CIL_0007VK CIL_0007VK_0002 VISTA 4:75400793-76001396
CIL_0007LL CIL_0007LL_0002 UCNEbase 4:75700943-76138737
CIL_0005UW CIL_0005UW_0003 CGP 4:75941238-80851719

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0007157 IDA heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016021 IEA integral component of membrane
GO:0030182 IDA neuron differentiation
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0050775 IDA positive regulation of dendrite morphogenesis
GO:0050839 IPI cell adhesion molecule binding
GO:0070062 IEA extracellular vesicular exosome
GO:0097105 IDA presynaptic membrane assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019945 ptprdb protein tyrosine phosphatase, receptor type, D, b protein_coding Danio_rerio
ENSG00000153707 PTPRD protein tyrosine phosphatase, receptor type, D protein_coding Homo_sapiens

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