C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cullin 4B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158290 CUL4B 9606 - X:120524609-120575794 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336592 CUL4B-004 120526396-120561440 protein_coding
  ENST00000371322 CUL4B-003 120524609-120560700 protein_coding
  ENST00000371323 CUL4B-007 120543746-120559943 protein_coding
  ENST00000404115 CUL4B-001 120526641-120575794 protein_coding
  ENST00000467641 CUL4B-005 120557917-120561302 processed_transcript
  ENST00000486604 CUL4B-002 120571176-120575524 processed_transcript
  ENST00000497616 CUL4B-006 120532336-120538547 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336592ENST00000371322ENST00000404115
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336592 4.337±0.00 N/A 1.711±0.00 4.075±0.00 5.629±0.00 N/A 0.664±0.00 5.181±0.00 3.488±0.00 4.793±0.00 1.206±0.00 4.316±0.00 N/A N/A
ENST00000371322 11.143±0.00 7.854±0.00 0.550±0.00 3.702±0.95 4.705±2.75 8.755±5.17 2.630±0.00 7.905±0.00 3.318±2.42 4.309±2.37 0.833±0.78 5.644±1.77 3.188±1.34 15.359±0.00
ENST00000404115 N/A N/A 0.810±0.00 N/A N/A N/A N/A N/A N/A 1.175±0.00 0.334±0.00 N/A N/A 14.205±9.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00016X CIL_00016X_0002 CGP X:120427827-120575794
CIL_0000GD CIL_0000GD_0002 CGP X:120524609-120621074

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003684 IDA damaged DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007049 NAS cell cycle
GO:0031461 IEA cullin-RING ubiquitin ligase complex
GO:0031465 IDA Cul4B-RING E3 ubiquitin ligase complex
GO:0031625 IEA ubiquitin protein ligase binding
GO:0035518 IDA histone H2A monoubiquitination
GO:0045732 IEA positive regulation of protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0070914 IDA UV-damage excision repair
GO:1900087 IEA positive regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060510 cul4b cullin 4B protein_coding Danio_rerio
ENSMUSG00000031095 Cul4b cullin 4B protein_coding Mus_musculus

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