C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cullin 4B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031095 Cul4b 10090 - X:38533274-38576196 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000016681 Cul4b-004 38533274-38564525 protein_coding
  ENSMUST00000050083 Cul4b-003 38533574-38576183 protein_coding
  ENSMUST00000115118 Cul4b-001 38533274-38576196 protein_coding
  ENSMUST00000147129 Cul4b-002 38533570-38564662 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000016681ENSMUST00000050083ENSMUST00000115118ENSMUST00000147129
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000016681 0.942±0.14 1.268±0.36 N/A 1.897±0.72 0.699±0.23 0.459±0.26 1.363±0.44 0.725±0.22 1.008±0.30 0.545±0.05 3.185±1.13 11.372±0.00 N/A
ENSMUST00000050083 2.064±0.00 1.449±0.24 N/A 1.707±0.19 0.854±0.16 N/A 1.960±0.45 1.579±0.41 1.210±0.33 N/A 2.017±1.08 29.122±12.57 4.857±3.14
ENSMUST00000115118 N/A N/A N/A N/A 0.989±0.23 0.527±0.18 N/A N/A N/A N/A N/A 14.649±6.20 5.153±0.57
ENSMUST00000147129 0.675±0.00 0.959±0.21 2.644±0.00 1.058±0.37 0.791±0.23 0.412±0.00 1.667±0.01 0.508±0.07 1.245±0.49 N/A 1.348±0.48 12.905±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00016X CIL_00016X_0003 CGP X:38401357-38576196
CIL_0000GD CIL_0000GD_0003 CGP X:38533274-38613426

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003684 IEA damaged DNA binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007049 IEA cell cycle
GO:0031461 IEA cullin-RING ubiquitin ligase complex
GO:0031465 ISS Cul4B-RING E3 ubiquitin ligase complex
GO:0031625 IEA ubiquitin protein ligase binding
GO:0035518 IEA histone H2A monoubiquitination
GO:0045732 IMP positive regulation of protein catabolic process
GO:0070062 IEA extracellular vesicular exosome
GO:0070914 IEA UV-damage excision repair
GO:1900087 IMP positive regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060510 cul4b cullin 4B protein_coding Danio_rerio
ENSG00000158290 CUL4B cullin 4B protein_coding Homo_sapiens

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