C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDC42 effector protein (Rho GTPase binding) 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179604 CDC42EP4 9606 - 17:73283624-73312175 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335793 CDC42EP4-001 73283624-73312175 protein_coding
  ENST00000439510 CDC42EP4-003 73283625-73311993 protein_coding
  ENST00000578516 CDC42EP4-005 73311054-73312005 processed_transcript
  ENST00000579611 CDC42EP4-004 73286282-73312001 protein_coding
  ENST00000580315 CDC42EP4-006 73286119-73311408 protein_coding
  ENST00000581014 CDC42EP4-009 73285178-73311997 protein_coding
  ENST00000581045 CDC42EP4-007 73286518-73310198 processed_transcript
  ENST00000582303 CDC42EP4-008 73306698-73309895 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000335793ENST00000439510ENST00000579611ENST00000580315
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000335793 43.545±0.00 16.873±0.00 N/A 10.685±8.90 9.265±7.69 13.215±11.31 8.084±6.15 5.778±3.91 2.866±2.00 10.153±8.71 5.262±0.00 35.574±21.37 21.003±0.91 11.923±0.00
ENST00000439510 34.887±0.00 13.384±0.00 N/A 12.924±11.25 17.413±0.00 15.901±0.00 N/A 9.822±0.00 2.886±0.60 4.565±3.87 1.037±0.00 4.063±0.74 7.070±1.41 5.979±4.35
ENST00000579611 N/A N/A 5.056±0.00 N/A N/A N/A N/A N/A N/A N/A 1.741±0.00 N/A N/A N/A
ENST00000580315 N/A N/A N/A N/A N/A 3.978±0.00 N/A N/A 6.437±0.00 N/A N/A 5.570±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007R4 CIL_0007R4_0001 VISTA 17:72990906-73592358
CIL_0008QM CIL_0008QM_0001 VISTA 17:73240460-73843108
CIL_00073C CIL_00073C_0001 CGP 17:73248449-73312175
CIL_0003AC CIL_0003AC_0002 CGP 17:73283624-73644089

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007266 IEA Rho protein signal transduction
GO:0008360 IDA regulation of cell shape
GO:0015629 IDA actin cytoskeleton
GO:0015630 IDA microtubule cytoskeleton
GO:0017049 NAS GTP-Rho binding
GO:0031274 IDA positive regulation of pseudopodium assembly
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039704 cdc42ep4a CDC42 effector protein (Rho GTPase binding) 4a protein_coding Danio_rerio
ENSDARG00000045036 cdc42ep4b CDC42 effector protein (Rho GTPase binding) 4b protein_coding Danio_rerio
ENSMUSG00000041598 Cdc42ep4 CDC42 effector protein (Rho GTPase binding) 4 protein_coding Mus_musculus

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