C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SET domain containing (lysine methyltransferase) 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000402868 SETD8-001 ENSG00000183955 9606 + 12:123383773-123409358 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000402868
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000402868 1.324±0.00 3.070±0.00 3.057±0.00 2.347±0.00 1.355±0.00 1.213±0.91 1.094±0.00 0.462±0.09 1.213±0.49 1.367±0.00 4.899±1.46 3.920±0.73 3.635±1.85

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000665 CIL_000665_0001 CGP 12:123289109-123409358
CIL_0003J0 CIL_0003J0_0001 CGP 12:123383773-123436717

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0002039 IPI p53 binding
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005694 IEA chromosome
GO:0005730 IDA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0007067 IEA mitotic nuclear division
GO:0016279 IDA protein-lysine N-methyltransferase activity
GO:0018024 IDA:IEA histone-lysine N-methyltransferase activity
GO:0018026 IDA peptidyl-lysine monomethylation
GO:0034968 IEA histone lysine methylation
GO:0043516 IMP regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045892 IDA negative regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000059580 Setd8-001 protein_coding Mus_musculus 0 1493
ENSMUST00000147969 Setd8-003 processed_transcript Mus_musculus 0 1376
ENSMUST00000100709 Setd8-002 protein_coding Mus_musculus 0 1210
ENSMUST00000154031 Setd8-006 processed_transcript Mus_musculus 0 1046
ENSMUST00000121113 Gm8770-001 processed_pseudogene Mus_musculus 0 887
ENSMUST00000125588 Setd8-010 retained_intron Mus_musculus 0 785
ENSMUST00000134826 Setd8-004 retained_intron Mus_musculus 0 597
ENSMUST00000138766 Setd8-005 processed_transcript Mus_musculus 0 590
ENSMUST00000121929 Gm11424-001 processed_pseudogene Mus_musculus 0 569
ENSMUST00000135667 Setd8-009 retained_intron Mus_musculus 0 564
ENSMUST00000143722 Setd8-008 processed_transcript Mus_musculus 0 403

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