C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin specific peptidase 7 (herpes virus-associated)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000187555 USP7 9606 - 16:8892094-8964514 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344836 USP7-001 8892094-8963484 protein_coding
  ENST00000381886 USP7-004 8893788-8936729 protein_coding
  ENST00000542333 USP7-003 8902143-8949653 nonsense_mediated_decay
  ENST00000562051 USP7-016 8899150-8900131 retained_intron
  ENST00000562615 USP7-018 8897064-8898720 retained_intron
  ENST00000563043 USP7-022 8898594-8901205 nonsense_mediated_decay
  ENST00000563085 USP7-002 8895045-8956380 protein_coding
  ENST00000563961 USP7-006 8892772-8963422 nonsense_mediated_decay
  ENST00000564117 USP7-011 8921177-8935856 protein_coding
  ENST00000565455 USP7-005 8893940-8936673 nonsense_mediated_decay
  ENST00000565883 USP7-019 8895084-8898544 retained_intron
  ENST00000566004 USP7-010 8920405-8956380 protein_coding
  ENST00000566131 USP7-015 8899580-8900920 retained_intron
  ENST00000566224 USP7-012 8923307-8935758 processed_transcript
  ENST00000566273 USP7-009 8921160-8962612 protein_coding
  ENST00000567113 USP7-020 8895059-8897254 retained_intron
  ENST00000567329 USP7-013 8902139-8904522 retained_intron
  ENST00000567692 USP7-021 8899175-8901185 nonsense_mediated_decay
  ENST00000569230 USP7-008 8920443-8964514 protein_coding
  ENST00000569448 USP7-017 8899307-8901219 retained_intron
  ENST00000570256 USP7-014 8901933-8904533 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000344836ENST00000381886ENST00000542333ENST00000563961
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000344836 4.192±0.00 6.097±0.00 1.943±0.00 4.554±2.46 3.667±0.61 5.204±0.00 2.367±0.00 2.761±0.00 3.880±2.50 1.946±0.46 2.973±1.36 6.862±3.36 4.385±0.88 4.602±0.00
ENST00000381886 8.910±0.00 5.608±0.00 0.984±0.00 5.179±2.83 5.476±1.44 6.608±0.00 6.526±0.00 2.853±1.09 4.031±0.00 2.920±0.00 9.959±0.00 5.589±0.81 4.227±0.46 20.181±3.21
ENST00000542333 N/A N/A N/A N/A 3.864±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 46.491±0.00
ENST00000563961 10.338±0.00 10.881±0.00 1.038±0.00 12.672±0.00 5.885±3.53 8.446±3.05 4.310±3.19 10.911±0.00 6.285±0.00 5.719±0.00 7.927±5.26 12.425±7.55 12.831±8.34 30.549±12.53

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000EV CIL_0000EV_0001 CGP 16:8852942-8964514
CIL_0000EN CIL_0000EN_0001 CGP 16:8892094-9121640

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002039 IDA p53 binding
GO:0004197 IMP cysteine-type endopeptidase activity
GO:0004221 IMP ubiquitin thiolesterase activity
GO:0004843 IMP ubiquitin-specific protease activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006283 IMP transcription-coupled nucleotide-excision repair
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007275 IEA multicellular organismal development
GO:0008022 IPI protein C-terminus binding
GO:0008134 IPI transcription factor binding
GO:0008234 IEA cysteine-type peptidase activity
GO:0010216 IMP maintenance of DNA methylation
GO:0016032 IEA viral process
GO:0016579 IMP protein deubiquitination
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0051090 IDA regulation of sequence-specific DNA binding transcription factor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073710 usp7 ubiquitin specific peptidase 7 (herpes virus-associated) protein_coding Danio_rerio
ENSMUSG00000022710 Usp7 ubiquitin specific peptidase 7 protein_coding Mus_musculus

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