C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor corepressor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196498 NCOR2 9606 - 12:124324415-124567589 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356219 NCOR2-201 124324416-124422554 protein_coding
  ENST00000404121 NCOR2-202 124324416-124422554 protein_coding
  ENST00000404621 NCOR2-002 124324415-124535603 protein_coding
  ENST00000405201 NCOR2-005 124324415-124495252 protein_coding
  ENST00000413172 NCOR2-018 124325420-124327585 protein_coding
  ENST00000418829 NCOR2-017 124325380-124332345 protein_coding
  ENST00000420698 NCOR2-004 124419959-124518294 protein_coding
  ENST00000429285 NCOR2-001 124324598-124535603 protein_coding
  ENST00000440187 NCOR2-013 124337104-124341863 protein_coding
  ENST00000440337 NCOR2-015 124328532-124333256 protein_coding
  ENST00000443451 NCOR2-022 124325386-124334646 retained_intron
  ENST00000448008 NCOR2-019 124430641-124483769 protein_coding
  ENST00000448614 NCOR2-009 124372460-124388824 protein_coding
  ENST00000453428 NCOR2-012 124340007-124342055 protein_coding
  ENST00000458234 NCOR2-003 124346593-124567464 protein_coding
  ENST00000461081 NCOR2-006 124331475-124336392 retained_intron
  ENST00000464377 NCOR2-016 124326123-124327659 retained_intron
  ENST00000473999 NCOR2-011 124347402-124348940 retained_intron
  ENST00000474079 NCOR2-014 124334344-124335181 retained_intron
  ENST00000493859 NCOR2-010 124355059-124356685 retained_intron
  ENST00000494460 NCOR2-007 124429395-124430641 retained_intron
  ENST00000536195 NCOR2-020 124354837-124356850 retained_intron
  ENST00000542565 NCOR2-008 124486374-124567589 retained_intron
  ENST00000542927 NCOR2-024 124430610-124483774 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356219ENST00000404121ENST00000404621ENST00000405201ENST00000420698ENST00000429285ENST00000443451ENST00000458234
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356219 N/A 6.195±0.00 N/A 4.425±0.00 1.227±0.00 6.596±6.01 N/A N/A N/A N/A N/A 49.590±0.00 N/A 4.299±0.00
ENST00000404121 9.507±0.00 5.847±0.00 0.705±0.00 4.561±0.00 10.422±0.00 N/A 7.874±0.00 N/A N/A 0.565±0.00 N/A N/A 5.714±0.78 6.405±0.00
ENST00000404621 17.490±0.00 10.683±0.00 N/A 3.925±3.32 10.206±0.00 13.683±0.00 N/A N/A 1.524±0.54 3.812±2.85 17.926±0.00 23.835±22.63 4.116±0.15 4.621±3.09
ENST00000405201 7.788±0.00 N/A 0.476±0.00 4.550±3.76 6.267±0.00 N/A N/A 3.530±0.00 1.154±0.00 7.910±0.00 N/A 12.948±5.21 3.997±2.13 3.398±0.09
ENST00000420698 N/A N/A 2.714±0.00 3.512±0.00 4.184±0.00 2.076±0.00 3.297±0.00 2.029±0.00 6.424±0.00 2.420±0.00 4.094±0.00 23.201±16.32 N/A 5.111±0.00
ENST00000429285 N/A N/A N/A N/A N/A 0.365±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000443451 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 172.872±0.00 60.085±0.00 25.644±0.00
ENST00000458234 N/A N/A N/A N/A N/A 1.106±0.00 N/A 1.623±0.00 1.622±0.00 1.085±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000399 CIL_000399_0001 CGP 12:124324415-124882668

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IEA histone deacetylase complex
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0001012 IEA RNA polymerase II regulatory region DNA binding
GO:0001701 IEA in utero embryonic development
GO:0003007 IEA heart morphogenesis
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003714 IMP transcription corepressor activity
GO:0005112 IPI Notch binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0007595 IEA lactation
GO:0010243 IEA response to organonitrogen compound
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016363 IDA nuclear matrix
GO:0016604 IDA nuclear body
GO:0016922 IEA ligand-dependent nuclear receptor binding
GO:0017053 IDA transcriptional repressor complex
GO:0021537 IEA telencephalon development
GO:0021846 IEA cell proliferation in forebrain
GO:0030900 IEA forebrain development
GO:0032355 IEA response to estradiol
GO:0032403 IEA protein complex binding
GO:0035259 IEA glucocorticoid receptor binding
GO:0042593 IEA glucose homeostasis
GO:0042698 IEA ovulation cycle
GO:0042826 IPI histone deacetylase binding
GO:0042974 IEA retinoic acid receptor binding
GO:0043565 IEA sequence-specific DNA binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045599 IEA negative regulation of fat cell differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046965 IEA retinoid X receptor binding
GO:0047485 IPI protein N-terminus binding
GO:0050872 IEA white fat cell differentiation
GO:0060206 IEA estrous cycle phase
GO:0060509 IEA Type I pneumocyte differentiation
GO:0072365 IMP regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000966 ncor2 nuclear receptor co-repressor 2 protein_coding Danio_rerio
ENSMUSG00000029478 Ncor2 nuclear receptor co-repressor 2 protein_coding Mus_musculus

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