C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor co-repressor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029478 Ncor2 10090 - 5:125017153-125179219 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055256 Ncor2-003 125017835-125124900 protein_coding
  ENSMUST00000086083 Ncor2-004 125017162-125179053 protein_coding
  ENSMUST00000111393 Ncor2-001 125017155-125179180 protein_coding
  ENSMUST00000111394 Ncor2-008 125017835-125179202 protein_coding
  ENSMUST00000111398 Ncor2-002 125017153-125179219 protein_coding
  ENSMUST00000111402 Ncor2-201 125017153-125179214 protein_coding
  ENSMUST00000125053 Ncor2-007 125017153-125042812 protein_coding
  ENSMUST00000130742 Ncor2-010 125025102-125026087 retained_intron
  ENSMUST00000134404 Ncor2-005 125030800-125058400 protein_coding
  ENSMUST00000134819 Ncor2-009 125025096-125026924 protein_coding
  ENSMUST00000138890 Ncor2-012 125018313-125025196 protein_coding
  ENSMUST00000144354 Ncor2-011 125018233-125023220 retained_intron
  ENSMUST00000149968 Ncor2-006 125047802-125055988 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086083ENSMUST00000111393ENSMUST00000111398ENSMUST00000111402ENSMUST00000125053ENSMUST00000138890
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086083 0.620±0.00 3.469±0.00 N/A 7.378±6.05 1.328±0.66 N/A 0.648±0.00 0.598±0.02 0.640±0.31 N/A 2.235±0.36 7.275±6.66 4.646±0.00 1.032±0.00
ENSMUST00000111393 N/A N/A N/A 13.791±0.00 N/A N/A N/A N/A N/A N/A N/A 15.431±11.68 7.033±1.42 2.467±0.00
ENSMUST00000111398 2.075±0.89 8.844±1.42 0.652±0.00 3.135±2.07 2.726±2.20 1.600±0.34 1.674±0.52 1.645±0.40 0.474±0.18 2.968±1.00 2.152±0.57 3.578±0.44 1.290±0.11 1.651±0.64
ENSMUST00000111402 0.897±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.966±0.15 4.633±3.10 N/A N/A
ENSMUST00000125053 1.974±0.50 14.440±0.96 3.114±2.34 4.015±2.69 3.407±1.90 3.561±1.63 2.104±0.97 1.652±0.68 0.737±0.39 3.911±0.63 4.233±0.62 4.187±0.77 17.592±14.84 N/A
ENSMUST00000138890 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 51.550±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004PN CIL_0004PN_0002 CGP 5:125003447-125179219
CIL_000399 CIL_000399_0002 CGP 5:125017153-125341094

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IDA histone deacetylase complex
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0001012 IEA RNA polymerase II regulatory region DNA binding
GO:0001701 IMP in utero embryonic development
GO:0003007 IGI heart morphogenesis
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003714 IMP transcription corepressor activity
GO:0005112 IEA Notch binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007595 IEA lactation
GO:0010243 IEA response to organonitrogen compound
GO:0016020 IEA membrane
GO:0016363 IEA nuclear matrix
GO:0016604 IDA nuclear body
GO:0016922 IEA ligand-dependent nuclear receptor binding
GO:0017053 IEA transcriptional repressor complex
GO:0021537 IMP telencephalon development
GO:0021846 IMP cell proliferation in forebrain
GO:0030900 IMP forebrain development
GO:0032355 IEA response to estradiol
GO:0032403 IEA protein complex binding
GO:0035259 IEA glucocorticoid receptor binding
GO:0042593 IMP glucose homeostasis
GO:0042698 IEA ovulation cycle
GO:0042826 IEA histone deacetylase binding
GO:0042974 IEA retinoic acid receptor binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045599 IMP negative regulation of fat cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046965 IEA retinoid X receptor binding
GO:0047485 IEA protein N-terminus binding
GO:0050872 IMP white fat cell differentiation
GO:0060206 IEA estrous cycle phase
GO:0060509 IGI Type I pneumocyte differentiation
GO:0072365 IEA regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000966 ncor2 nuclear receptor co-repressor 2 protein_coding Danio_rerio
ENSG00000196498 NCOR2 nuclear receptor corepressor 2 protein_coding Homo_sapiens

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