C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family B (MDR/TAP), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197150 ABCB8 9606 + 7:151028422-151047782 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000297504 ABCB8-003 151028450-151045562 protein_coding
  ENST00000358849 ABCB8-005 151028423-151047782 protein_coding
  ENST00000461373 ABCB8-012 151028423-151033842 protein_coding
  ENST00000462605 ABCB8-016 151028450-151033242 retained_intron
  ENST00000466514 ABCB8-007 151028450-151045562 nonsense_mediated_decay
  ENST00000466956 ABCB8-017 151028450-151034599 processed_transcript
  ENST00000469410 ABCB8-021 151028657-151033060 processed_transcript
  ENST00000470645 ABCB8-004 151028450-151042030 nonsense_mediated_decay
  ENST00000471796 ABCB8-015 151028450-151033034 processed_transcript
  ENST00000472698 ABCB8-018 151028473-151031626 processed_transcript
  ENST00000477092 ABCB8-010 151028467-151037570 protein_coding
  ENST00000477719 ABCB8-009 151028464-151037524 protein_coding
  ENST00000482309 ABCB8-006 151028426-151045409 nonsense_mediated_decay
  ENST00000482899 ABCB8-011 151037688-151045562 retained_intron
  ENST00000488370 ABCB8-019 151028476-151033698 processed_transcript
  ENST00000488551 ABCB8-020 151028476-151034547 nonsense_mediated_decay
  ENST00000488826 ABCB8-013 151028437-151033750 processed_transcript
  ENST00000489192 ABCB8-014 151028438-151034551 nonsense_mediated_decay
  ENST00000491920 ABCB8-023 151035619-151037586 protein_coding
  ENST00000493338 ABCB8-022 151032930-151034597 processed_transcript
  ENST00000498578 ABCB8-008 151028462-151045563 protein_coding
  ENST00000542328 ABCB8-201 151028422-151047782 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000297504ENST00000358849ENST00000466514ENST00000472698ENST00000477092ENST00000482309ENST00000482899ENST00000491920ENST00000493338ENST00000498578
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000297504 1.783±0.00 4.220±0.00 0.587±0.00 2.629±0.00 2.717±0.00 N/A N/A N/A N/A 2.288±0.00 1.030±0.00 N/A 7.380±2.04 1.958±0.00
ENST00000358849 N/A N/A N/A 1.986±0.00 0.836±0.00 0.260±0.00 0.817±0.58 N/A 1.189±0.00 0.709±0.00 0.196±0.00 4.041±0.38 1.954±0.34 2.571±1.66
ENST00000466514 N/A 2.402±0.00 N/A 2.149±0.00 2.288±0.00 2.465±0.00 N/A 4.026±0.00 5.477±0.00 N/A N/A 6.510±0.00 N/A N/A
ENST00000472698 N/A N/A N/A N/A N/A N/A N/A 0.860±0.00 N/A N/A N/A N/A N/A N/A
ENST00000477092 1.022±0.00 N/A N/A 2.669±0.00 0.530±0.00 N/A 0.755±0.00 4.182±0.00 N/A N/A N/A 5.656±0.00 3.564±0.00 N/A
ENST00000482309 0.863±0.00 N/A N/A N/A N/A N/A 2.222±0.00 0.747±0.00 2.769±0.00 N/A N/A 4.144±0.76 8.130±1.90 2.106±0.00
ENST00000482899 N/A 0.945±0.00 0.404±0.00 N/A 0.521±0.00 N/A N/A 0.202±0.00 N/A N/A N/A 1.307±0.00 N/A N/A
ENST00000491920 N/A N/A N/A N/A N/A N/A N/A 0.903±0.00 N/A N/A N/A N/A N/A N/A
ENST00000493338 N/A N/A 1.542±0.00 N/A N/A N/A N/A N/A 2.561±0.00 N/A N/A N/A N/A N/A
ENST00000498578 1.554±0.00 N/A N/A N/A 3.960±0.00 1.716±0.00 N/A 6.324±0.00 6.087±0.00 N/A 1.380±0.00 3.372±1.80 10.625±2.54 2.198±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008T1 CIL_0008T1_0001 VISTA 7:150668461-151272977
CIL_0004O6 CIL_0004O6_0001 CGP 7:151012209-151047782
CIL_0004O7 CIL_0004O7_0001 CGP 7:151028422-151052756

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005215 TAS transporter activity
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005739 IDA mitochondrion
GO:0005740 TAS mitochondrial envelope
GO:0005743 IEA mitochondrial inner membrane
GO:0006200 IEA ATP catabolic process
GO:0006810 TAS:IEA transport
GO:0016020 TAS membrane
GO:0016021 IBA:IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0042626 IBA:IEA ATPase activity, coupled to transmembrane movement of substances
GO:0043190 TAS ATP-binding cassette (ABC) transporter complex
GO:0055085 IBA:IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056672 abcb8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 protein_coding Danio_rerio
ENSMUSG00000028973 Abcb8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 protein_coding Mus_musculus

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