C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysophosphatidic acid receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198121 LPAR1 9606 - 9:110873263-111038458 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358883 LPAR1-003 110874177-111038085 protein_coding
  ENST00000374430 LPAR1-002 110873778-110999466 protein_coding
  ENST00000374431 LPAR1-001 110873263-111038043 protein_coding
  ENST00000441240 LPAR1-004 110941668-111038458 protein_coding
  ENST00000541779 LPAR1-201 110874321-111036207 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358883ENST00000374430ENST00000374431ENST00000441240ENST00000541779
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358883 N/A N/A 2.121±0.00 N/A 3.302±0.00 N/A 1.161±0.00 0.531±0.00 4.854±0.00 1.681±0.00 0.647±0.00 2.069±0.00 1.520±0.00 N/A
ENST00000374430 N/A N/A N/A 8.739±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000374431 3.697±0.00 15.311±0.00 N/A 7.903±4.23 0.904±0.00 12.812±10.24 1.987±0.00 2.883±2.76 1.426±0.00 4.381±0.00 2.231±0.00 1.903±1.70 6.438±0.77 6.598±3.68
ENST00000441240 N/A N/A N/A 12.566±0.00 3.991±0.00 8.234±0.00 1.962±0.00 N/A 13.988±0.00 7.348±0.00 2.265±0.00 4.162±0.00 N/A N/A
ENST00000541779 N/A N/A N/A N/A N/A N/A 0.877±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00016H CIL_00016H_0001 CGP 9:110668771-111038458
CIL_00093E CIL_00093E_0001 VISTA 9:110861070-111465765
CIL_00016L CIL_00016L_0001 CGP 9:110873263-111328520

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001965 IEA G-protein alpha-subunit binding
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005543 IEA phospholipid binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007204 TAS positive regulation of cytosolic calcium ion concentration
GO:0009986 IDA cell surface
GO:0010942 IEA positive regulation of cell death
GO:0010977 IEA negative regulation of neuron projection development
GO:0016021 IEA integral component of membrane
GO:0022008 IEA neurogenesis
GO:0030139 IDA endocytic vesicle
GO:0030165 IEA PDZ domain binding
GO:0032060 IEA bleb assembly
GO:0035025 IEA positive regulation of Rho protein signal transduction
GO:0042552 IEA myelination
GO:0043065 IEA positive regulation of apoptotic process
GO:0043123 IEP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043197 IEA dendritic spine
GO:0043198 IEA dendritic shaft
GO:0043410 IEA positive regulation of MAPK cascade
GO:0051482 IEA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0060999 IEA positive regulation of dendritic spine development
GO:0070915 IEA lysophosphatidic acid receptor activity
GO:0071453 IEA cellular response to oxygen levels
GO:0071673 IEA positive regulation of smooth muscle cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044213 lpar1 lysophosphatidic acid receptor 1 protein_coding Danio_rerio
ENSMUSG00000038668 Lpar1 lysophosphatidic acid receptor 1 protein_coding Mus_musculus

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