C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCCTC-binding factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005698 Ctcf 10090 + 8:105636568-105682922 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005841 Ctcf-001 105636579-105682922 protein_coding
  ENSMUST00000128510 Ctcf-003 105636935-105664134 processed_transcript
  ENSMUST00000129388 Ctcf-004 105637066-105663851 processed_transcript
  ENSMUST00000132679 Ctcf-002 105636568-105681647 processed_transcript
  ENSMUST00000137735 Ctcf-005 105676011-105679567 processed_transcript
  ENSMUST00000156436 Ctcf-006 105676011-105680617 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005841ENSMUST00000128510ENSMUST00000129388ENSMUST00000132679ENSMUST00000137735ENSMUST00000156436
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005841 4.593±2.83 2.918±0.70 8.186±0.72 14.198±9.13 3.396±1.34 2.584±0.78 2.628±0.15 3.574±1.62 6.970±5.53 6.583±1.60 4.136±2.72 4.923±3.04 8.399±0.67 1.895±0.50
ENSMUST00000128510 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.030±0.00
ENSMUST00000129388 N/A 1.982±0.62 N/A N/A N/A 2.181±0.11 N/A N/A N/A N/A N/A 2.529±0.64 N/A N/A
ENSMUST00000132679 1.828±0.32 2.466±0.44 3.561±0.00 4.967±0.00 1.977±0.20 3.782±0.90 1.749±0.10 3.067±0.72 3.862±1.64 3.811±0.59 N/A 4.058±1.90 5.528±2.32 1.262±0.00
ENSMUST00000137735 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 22.111±0.00
ENSMUST00000156436 N/A N/A N/A 21.647±0.00 N/A N/A N/A N/A N/A N/A N/A 51.008±0.00 31.885±20.80 7.514±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003LR CIL_0003LR_0003 CGP 8:105605229-105682922
CIL_0006LW CIL_0006LW_0003 CGP 8:105636568-105698178

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000775 IEA chromosome, centromeric region
GO:0000793 IEA condensed chromosome
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IEA nucleoplasm
GO:0005730 IEA nucleolus
GO:0006306 IDA DNA methylation
GO:0006349 IDA regulation of gene expression by genetic imprinting
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007059 IEA chromosome segregation
GO:0009048 TAS dosage compensation by inactivation of X chromosome
GO:0010216 IMP maintenance of DNA methylation
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0016568 IEA chromatin modification
GO:0016584 IEA nucleosome positioning
GO:0031060 IMP regulation of histone methylation
GO:0035065 IMP regulation of histone acetylation
GO:0040029 IEA regulation of gene expression, epigenetic
GO:0040030 IEA regulation of molecular function, epigenetic
GO:0043035 IEA chromatin insulator sequence binding
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056621 ctcf CCCTC-binding factor (zinc finger protein) protein_coding Danio_rerio
ENSG00000102974 CTCF CCCTC-binding factor (zinc finger protein) protein_coding Homo_sapiens

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