C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: CCCTC-binding factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000005841 Ctcf-001 ENSMUSG00000005698 10090 + 8:105636579-105682922 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005841
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005841 4.593±2.83 2.918±0.70 8.186±0.72 14.198±9.13 3.396±1.34 2.584±0.78 2.628±0.15 3.574±1.62 6.970±5.53 6.583±1.60 4.136±2.72 4.923±3.04 8.399±0.67 1.895±0.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003LR CIL_0003LR_0003 CGP 8:105605229-105682922
CIL_0006LW CIL_0006LW_0003 CGP 8:105636568-105698178

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000775 IEA chromosome, centromeric region
GO:0000793 IEA condensed chromosome
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IEA nucleoplasm
GO:0005730 IEA nucleolus
GO:0006306 IDA DNA methylation
GO:0006349 IDA regulation of gene expression by genetic imprinting
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007059 IEA chromosome segregation
GO:0009048 TAS dosage compensation by inactivation of X chromosome
GO:0010216 IMP maintenance of DNA methylation
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0016568 IEA chromatin modification
GO:0016584 IEA nucleosome positioning
GO:0031060 IMP regulation of histone methylation
GO:0035065 IMP regulation of histone acetylation
GO:0040029 IEA regulation of gene expression, epigenetic
GO:0040030 IEA regulation of molecular function, epigenetic
GO:0043035 IEA chromatin insulator sequence binding
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264010 CTCF-001 protein_coding Homo_sapiens 0 4752
ENST00000401394 CTCF-002 protein_coding Homo_sapiens 0 3097
ENST00000566078 CTCF-003 retained_intron Homo_sapiens 0 1397

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