C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005883 Spo11 10090 + 2:172977700-172993576 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050442 Spo11-001 172979849-172993576 protein_coding
  ENSMUST00000109125 Spo11-003 172979842-172993565 protein_coding
  ENSMUST00000109126 Spo11-002 172979849-172993567 protein_coding
  ENSMUST00000144044 Spo11-004 172977700-172993571 retained_intron
  ENSMUST00000156471 Spo11-005 172985877-172992053 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000050442ENSMUST00000109125ENSMUST00000109126ENSMUST00000144044ENSMUST00000156471
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000050442 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.425±0.00
ENSMUST00000109125 0.176±0.00 N/A N/A N/A N/A N/A 0.010±0.00 0.061±0.04 0.012±0.01 0.041±0.01 0.032±0.00 0.115±0.10 0.041±0.03 18.574±10.59
ENSMUST00000109126 N/A N/A N/A N/A N/A N/A N/A 0.065±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000144044 0.088±0.06 0.027±0.00 0.101±0.05 0.229±0.14 0.295±0.07 0.117±0.05 0.048±0.03 0.049±0.03 0.027±0.02 0.094±0.01 0.021±0.01 0.096±0.05 0.020±0.01 4.789±0.71
ENSMUST00000156471 N/A N/A N/A 0.209±0.00 N/A 0.384±0.14 0.065±0.00 0.124±0.05 N/A N/A 0.305±0.00 0.385±0.00 0.091±0.00 17.287±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YW CIL_0008YW_0002 VISTA 2:172561962-173164167
CIL_0008TD CIL_0008TD_0002 VISTA 2:172564603-173165839
CIL_0008HJ CIL_0008HJ_0002 VISTA 2:172734798-173336840
CIL_0008BA CIL_0008BA_0002 VISTA 2:172748983-173356071
CIL_0006IN CIL_0006IN_0003 CGP 2:172868012-172993576
CIL_0002XR CIL_0002XR_0002 CGP 2:172977700-173015739

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0000781 IDA chromosome, telomeric region
GO:0001541 IMP ovarian follicle development
GO:0003677 IEA DNA binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0007129 IMP synapsis
GO:0007131 IMP reciprocal meiotic recombination
GO:0007141 IMP male meiosis I
GO:0007286 IMP spermatid development
GO:0016787 IEA hydrolase activity
GO:0034502 IMP protein localization to chromosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013837 spo11 SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae) protein_coding Danio_rerio
ENSG00000054796 SPO11 SPO11 meiotic protein covalently bound to DSB protein_coding Homo_sapiens

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